High mobility group box chromosomal protein 1 as a nuclear protein, cytokine, and potential therapeutic target in arthritis

被引:80
作者
Ulloa, L [1 ]
Batliwalla, FM [1 ]
Andersson, U [1 ]
Gregersen, PK [1 ]
Tracey, KJ [1 ]
机构
[1] N Shore Univ Hosp, Long Isl Jewish Res Inst, Manhasset, NY 11030 USA
来源
ARTHRITIS AND RHEUMATISM | 2003年 / 48卷 / 04期
关键词
BASIC AMINO-ACIDS; NEURITE OUTGROWTH; BINDING PROTEIN; AMPHOTERIN; HMG-1; MICE; INFLAMMATION; ANTIBODIES; MEDIATOR; CELLS;
D O I
10.1002/art.10854
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:876 / 881
页数:6
相关论文
共 30 条
  • [1] Cutting edge: HMG-1 as a mediator of acute lung inflammation
    Abraham, E
    Arcaroli, J
    Carmody, A
    Wang, HC
    Tracey, KJ
    [J]. JOURNAL OF IMMUNOLOGY, 2000, 165 (06) : 2950 - 2954
  • [2] HMGB-1, a DNA-binding protein with cytokine activity, induces brain TNF and IL-6 production, and mediates anorexia and taste aversion
    Agnello, D
    Wang, HC
    Yang, H
    Tracey, KJ
    Ghezzi, P
    [J]. CYTOKINE, 2002, 18 (04) : 231 - 236
  • [3] High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    Andersson, U
    Wang, HC
    Palmblad, K
    Aveberger, AC
    Bloom, O
    Erlandsson-Harris, H
    Janson, A
    Kokkola, R
    Zhang, MH
    Yang, H
    Tracey, KJ
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 192 (04) : 565 - 570
  • [4] AYER LM, 1994, J RHEUMATOL, V21, P2071
  • [5] A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis
    Baugh, JA
    Chitnis, S
    Donnelly, SC
    Monteiro, J
    Lin, X
    Plant, BJ
    Wolfe, F
    Gregersen, PK
    Bucala, R
    [J]. GENES AND IMMUNITY, 2002, 3 (03) : 170 - 176
  • [6] Upwardly mobile proteins Workshop: The role of HMG proteins in chromatin structure, gene expression and neoplasia
    Bianchi, Marco E.
    Beltrame, Monica
    [J]. EMBO REPORTS, 2000, 1 (02) : 109 - 114
  • [7] Revised nomenclature for high mobility group (HMG) chromosomal proteins
    Bustin, M
    [J]. TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (03) : 152 - 153
  • [8] The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice
    Calogero, S
    Grassi, F
    Aguzzi, A
    Voigtländer, T
    Ferrier, P
    Ferrari, S
    Bianchi, ME
    [J]. NATURE GENETICS, 1999, 22 (03) : 276 - 280
  • [9] The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
    Degryse, B
    Bonaldi, T
    Scaffidi, P
    Müller, S
    Resnati, M
    Sanvito, F
    Arrigoni, G
    Bianchi, ME
    [J]. JOURNAL OF CELL BIOLOGY, 2001, 152 (06) : 1197 - 1206
  • [10] The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
    Gardella, S
    Andrei, C
    Ferrera, D
    Lotti, LV
    Torrisi, MR
    Bianchi, ME
    Rubartelli, A
    [J]. EMBO REPORTS, 2002, 3 (10) : 995 - 1001