Superhydrophobic silver film as a SERS substrate for the detection of uric acid and creatinine

被引：26
作者：
Lu, Yudong [1 ]
Wu, Changji [1 ]
You, Ruiyun [1 ]
Wu, Yang [1 ]
Shen, Huiying [1 ]
Zhu, Lanjin [1 ]
Feng, Shangyuan [2 ]
机构：
[1] Fujian Normal Univ, Fujian Key Lab Polymer Mat, Coll Chem & Mat Sci, Fuzhou 350007, Fujian, Peoples R China
[2] Fujian Normal Univ, Key Lab Optoelect Sci & Technol Med, Fujian Prov Key Lab Photon Technol, Minist Educ, Fuzhou 350007, Fujian, Peoples R China
来源：
BIOMEDICAL OPTICS EXPRESS | 2018年 / 9卷 / 10期
基金：
中国国家自然科学基金;
关键词：
ENHANCED RAMAN-SCATTERING; SURFACE; SPECTROSCOPY; DISEASE; PROTEIN; WATER;
D O I：
10.1364/BOE.9.004988
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Superhydrophobic silver films were fabricated by silver-mirror reaction and surface functionalization with thiol. The thiol-functionalization significantly improved the hydrophobic property of the Ag films (AFS), and their contact angle values slightly increased with the extension of a thiol alkyl chain, reaching about 160 degrees. The surface-enhanced Raman scattering (SERS) detection capacity of these films were investigated, and AFS-Dodcc showed the best substrate for R6G molecule detection with the concentration limit of 10(-11) M. AFS functionalized with dodecanethiol (AFS-Dodec) was applied for the SERS detection of uric acid and creatinine, it exhibited good linear dependence relationship between the Raman intensity and analyte concentration in the concentration range of 5 similar to 1000 mu M. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码：4988 / 4997
页数：10
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