Shorter Adult Height is Associated with Poorer Cognitive Performance in Elderly Men with Type II Diabetes

被引：13

作者：

West, Rebecca K. ^{[1
]}

Ravona-Springer, Ramit ^{[2
]}

Heymann, Anthony ^{[4
]}

Schmeidler, James ^{[1
]}

Leroith, Derek ^{[5
]}

Koifman, Keren ^{[2
]}

Guerrero-Berroa, Elizabeth ^{[1
]}

Preiss, Rachel ^{[2
]}

Hoffman, Hadas ^{[2
]}

Silverman, Jeremy M. ^{[1
,3
]}

Beeri, Michal Schnaider ^{[1
,2
]}

机构：

[1] Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA

[2] Sheba Med Ctr, Joseph Sagol Neurosci Ctr, Ramat Gan, Israel

[3] James J Peters Vet Affairs Med Ctr, Bronx, NY USA

[4] Maccabi Healthcare Serv, Tel Aviv, Israel

[5] Icahn Sch Med Mt Sinai, Dept Med, Div Med Endocrinol Diabet & Bone Dis, New York, NY 10029 USA

来源：

JOURNAL OF ALZHEIMERS DISEASE | 2015年 / 44卷 / 03期

关键词：

Cognitive performance; height; risk factors; type 2 diabetes mellitus; vascular dementia; CORONARY-HEART-DISEASE; ALZHEIMERS-DISEASE; RISK-FACTORS; BODY HEIGHT; LATE-LIFE; LEG LENGTH; CIRCUMFERENCE; EDUCATION; DEMENTIA; IMPAIRMENT;

D O I：

10.3233/JAD-142049

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We studied the relationship of adult body height with five cognitive outcomes (executive functioning, semantic categorization, attention/working memory, episodic memory, and an overall cognition measure) in 897 cognitively normal elderly with type 2 diabetes. Regression analyses controlling for sociodemographic, cardiovascular, and diabetes-related risk factors and depression demonstrated that in males, shorter stature was associated with poorer executive functioning (p = 0.001), attention/working memory (p = 0.007), and overall cognition (p = 0.016), but not with episodic memory (p = 0.715) or semantic categorization (p = 0.948). No relationship between height and cognition was found for females. In cognitively normal type 2 diabetes male subjects, shorter stature, a surrogate for early-life stress and poor nutrition, was associated with cognitive functions.

引用

页码：927 / 935

页数：9

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