A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans

被引:10
作者
Eisen, A [1 ]
Sattah, M [1 ]
Gazitt, T [1 ]
Neal, K [1 ]
Szauter, P [1 ]
Lucchesi, J [1 ]
机构
[1] Emory Univ, Dept Biol, Atlanta, GA 30322 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1397卷 / 02期
关键词
helicase; translation initiation; gene evolution; (Drosophila);
D O I
10.1016/S0167-4781(97)00213-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have identified a novel Drosophila protein, DBF80, that exhibits significant similarity to mouse mDEAD5, yeast TIF1/2, and mammalian eIF-4A. DBP80 is a member of a subclass of DEAD-box proteins that contains a distinct domain. PX(I/R>ILLKR(E/D)EETLEGIKQ(F/Y)(F/Y), in addition to the seven canonical helicase domains. (C) 1998 Elsevier Science B.V.
引用
收藏
页码:131 / 136
页数:6
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