The effect of catalyst loading in copper-catalyzed cyclohexane functionalization by carbene insertion

被引：17

作者：

Caballero, Ana

Diaz-Requejo, M. Mar

Trofimenko, Swiatoslaw

Belderrain, Tomas R.

Perez, Pedro J.

机构：

[1] Univ Huelva, Dept Quim & Ciencia Mat, CSIC, Unidad Asociada Lab Catalisis Homogenea, E-21007 Huelva, Spain

[2] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA

来源：

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY | 2007年 / 18期

关键词：

copper; C-H activation; homogeneous catalysis; carbenes; N ligands;

D O I：

10.1002/ejic.200600811

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A study of the variables that affect the insertion of the :CHCO2Et group (formed from ethyl diazocetate, EDA) into the C-H bonds of cyclohexane in the presence of a Tp(x)Cu complex as the catalyst (Tp(x) = trispyrazolylborate ligand) has demonstrated an anomalous effect of the catalyst loading. The use of low concentrations of catalyst produces an increase in the yield of the C-H activation product ethyl cyclohexaneacetate. This effect has also been found in the case of other less elaborated catalysts such as [Bp(Br3)Cu] or [(bipy)(2)Cu][I]. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007.

引用

页码：2848 / 2852

页数：5

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