A highly selective long-wavelength fluorescent probe for the detection of human carboxylesterase 2 and its biomedical applications

被引：82
作者：
Feng, Lei [1 ,2 ]
Liu, Zhao-Ming [2 ]
Xu, Liang [3 ]
Lv, Xia [2 ]
Ning, Jing [2 ]
Hou, Jie [4 ]
Ge, Guang-Bo [1 ,2 ]
Cui, Jing-Nan [1 ]
Yang, Ling [2 ]
机构：
[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian, Peoples R China
[2] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
[3] Dalian Univ Technol, Sch Chem, Dalian, Peoples R China
[4] Dalian Med Univ, Dalian 116044, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 93期
关键词：
LIVING CELLS; HUMAN LIVER; MAMMALIAN CARBOXYLESTERASES; CATALYTIC-PROPERTIES; IRINOTECAN; ACTIVATION; CPT-11; FLUOROPHORE; METABOLISM; PHARMACOKINETICS;
D O I：
10.1039/c4cc06642a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly selective long-wavelength fluorescent probe TCFB has been developed for the detection of hCE2. The probe can be used for real-time monitoring of hCE2 activity in complex biological systems.
引用
收藏
页码：14519 / 14522
页数：4
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