Nonoperative management of appendicitis in children

被引:39
作者
Lopez, Joseph J. [1 ,2 ]
Deans, Katherine J. [1 ,3 ]
Minneci, Peter C. [1 ,3 ]
机构
[1] Nationwide Childrens Hosp, Res Inst, Ctr Surg Outcomes Res, 611 Livingston Ave,Fac Off Bldg,Suite 3, Columbus, OH 43205 USA
[2] New York Med Coll, Dept Surg, Westchester Med Ctr, Valhalla, NY 10595 USA
[3] Nationwide Childrens Hosp, Dept Pediat Surg, Columbus, OH USA
关键词
antibiotics; appendectomy; appendicitis; children; nonoperative management; pediatric surgery; INTERVAL APPENDECTOMY; PERFORATED APPENDICITIS; LAPAROSCOPIC APPENDECTOMY; COMPLICATED APPENDICITIS; ANTIBIOTIC-TREATMENT; FAILURE; OUTCOMES; COHORT; TRIAL; SAFE;
D O I
10.1097/MOP.0000000000000487
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose of review The aim of this review is to summarize the recent literature investigating nonoperative management of uncomplicated and complicated appendicitis and highlight recent data establishing its safety and efficacy. Recent findings Recent studies and clinical trials have demonstrated the efficacy of nonoperative treatment of both uncomplicated and complicated appendicitis, defined as perforated appendicitis with or without formed abscess or phlegmon. Nonoperative management of uncomplicated appendicitis has been reported to be effective in approximately 71-94% of cases. In complicated appendicitis, treatment with antibiotics alone or antibiotics with interval appendectomy has been shown to be a well tolerated and reasonable treatment alternative. Summary Appendicitis is one of the most common surgical diagnoses in children. The standard of care for many years has been surgical appendectomy; however, it carries with it risks including bleeding, wound complications, injury to surrounding structures, and the potential need for reoperation. Nonoperative management of both uncomplicated and complicated appendicitis in children is well tolerated and efficacious in select populations.
引用
收藏
页码:358 / 362
页数:5
相关论文
共 24 条
[1]   Nonoperative treatment of acute appendicitis in children [J].
Abes, Musa ;
Petik, Buelent ;
Kazil, Selcuk .
JOURNAL OF PEDIATRIC SURGERY, 2007, 42 (08) :1439-1442
[2]   In-hospital Surgical Delay Does Not Increase the Risk for Perforated Appendicitis in Children A Single-center Retrospective Cohort Study [J].
Almstrom, Markus ;
Svensson, Jan F. ;
Patkova, Barbora ;
Svenningsson, Anna ;
Wester, Tomas .
ANNALS OF SURGERY, 2017, 265 (03) :616-621
[3]   Non-operative management of early, acute appendicitis in children: Is it safe and effective? [J].
Armstrong, Jeff ;
Merritt, Neil ;
Jones, Sarah ;
Scott, Leslie ;
Buetter, Andreana .
JOURNAL OF PEDIATRIC SURGERY, 2014, 49 (05) :782-785
[4]   Pediatric appendiceal ultrasound: accuracy, determinacy and clinical outcomes [J].
Binkovitz, Larry A. ;
Unsdorfer, Kyle M. L. ;
Thapa, Prabin ;
Kolbe, Amy B. ;
Hull, Nathan C. ;
Zingula, Shannon N. ;
Thomas, Kristen B. ;
Homme, James L. .
PEDIATRIC RADIOLOGY, 2015, 45 (13) :1934-1944
[5]   Early vs Interval Appendectomy for Children With Perforated Appendicitis [J].
Blakely, Martin L. ;
Williams, Regan ;
Dassinger, Melvin S. ;
Eubanks, James W., III ;
Fischer, Peter ;
Huang, Eunice Y. ;
Paton, Elizabeth ;
Culbreath, Barbara ;
Hester, Allison ;
Streck, Christian ;
Hixson, S. Douglas ;
Langham, Max R., Jr. .
ARCHIVES OF SURGERY, 2011, 146 (06) :660-665
[6]   Nonoperative treatment of suspected appendicitis in remote medical care environments: Implications for future spaceflight medical care [J].
Campbell, MR ;
Johnston, SL ;
Marshburn, T ;
Kane, J ;
Lugg, D .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2004, 198 (05) :822-830
[7]   Nonoperative Management of Appendicitis in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [J].
Findlay, John M. ;
el Kafsi, Jihene ;
Hammer, Clare ;
Gilmour, Jeffrey ;
Gillies, Richard S. ;
Maynard, Nicholas D. .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2016, 223 (06) :814-+
[8]   Should the non-operative management of appendicitis be the new standard of care? [J].
Gandy, Robert C. ;
Wang, Frank .
ANZ JOURNAL OF SURGERY, 2016, 86 (04) :228-231
[9]   Initial antibiotic treatment for acute simple appendicitis in children is safe: Short-term results from a multicenter, prospective cohort study [J].
Gorter, Ramon R. ;
van der Lee, Johanna H. ;
Cense, Huibert A. ;
Kneepkens, C. M. Frank ;
Wijnen, Marc H. W. A. ;
't Hof, Klaas H. In ;
Offringa, Martin ;
Heij, Hugo A. .
SURGERY, 2015, 157 (05) :916-923
[10]   Nonoperative treatment of acute appendicitis in children: A feasibility study [J].
Hartwich, Joseph ;
Luks, Francois I. ;
Watson-Smith, Debra ;
Kurkchubasche, Arlet G. ;
Muratore, Christopher S. ;
Wills, Hale E. ;
Tracy, Thomas F., Jr. .
JOURNAL OF PEDIATRIC SURGERY, 2016, 51 (01) :111-116