We study the Navier wall law for the two-dimensional initial boundary value problem of the Navier-Stokes equations in a domain with a rough boundary. The Navier wall law is verified for the initial data in C-1 class under the natural compatibility condition. Our proof relies on the boundary layer analysis and the L-infinity theory of the Navier-Stokes equations in the half space. (C) 2016 Elsevier Inc. All rights reserved.