(P,C) Cyclometalated Gold(III) Complexes: Highly Active Catalysts for the Hydroarylation of Alkynes

被引：44

作者：

Blons, Charlie ^{[1
]}

Mallet-Ladeira, Sonia ^{[2
]}

Amgoune, Abderrahmane ^{[1
]}

Bourissou, Didier ^{[1
]}

机构：

[1] Univ Paul Sabatier, LHFA, CNRS, UMR 5069, 118 Route Narbonne, F-31062 Toulouse 09, France

[2] Inst Chim Toulouse, FR 2599, 118 Route Narbonne, F-31062 Toulouse 09, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 36期

关键词：

alkynes; gold(III); homogeneous catalysis; hydroarylation; P-based ligands; C-H BONDS; OXIDATIVE ADDITION; GOLD COMPLEXES; INSERTION; ACTIVATION; FUNCTIONALIZATION; REACTIVITY; NORBORNENE; CHEMISTRY; OLEFINS;

D O I：

10.1002/anie.201807106

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first catalytic application of well-defined (P,C) cyclometalated gold(III) complexes is reported. The bench-stable bis(trifluoroacetyl) complexes 2a,b perform very well in the intermolecular hydroarylation of alkynes. The reaction is broad in scope, it proceeds within few hours at 25 degrees C at catalytic loadings of 0.1-5 mol%. The electron-rich arene adds across the C C bond with complete regio- and stereo-selectivity. The significance of well-defined gold(III) complexes and ligand design are highlighted in a powerful but challenging catalytic transformation.

引用

页码：11732 / 11736

页数：5

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