Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates

被引：50

作者：

McReynolds, Katherine D. ^{[1
]}

Gervay-Hague, Jacquelyn

机构：

[1] Calif State Univ Sacramento, Dept Chem, Sacramento, CA 95819 USA

[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

CHEMICAL REVIEWS | 2007年 / 107卷 / 05期

关键词：

D O I：

10.1021/cr0502652

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The host-associated carbohydrate-mediated entry processes of HIV-1 are reviewed. Topics covered include the current HIV/AIDS treatments and limitations, HIV-1 surface protein Gp 120 and its role in the viral entry of CD4-positive T-cells vial fusion, polyanionics polysaccharides as anti-HIV agents in CD4-positive cells, and HIV surface protein gp120 and its role in the viral entry of CD4-negative cells.

引用

页码：1533 / 1552

页数：20

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