Chemotherapeutic interventions targeting HIV interactions with host-associated carbohydrates

被引：50
作者：
McReynolds, Katherine D. [1 ]
Gervay-Hague, Jacquelyn
机构：
[1] Calif State Univ Sacramento, Dept Chem, Sacramento, CA 95819 USA
[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA
来源：
CHEMICAL REVIEWS | 2007年 / 107卷 / 05期
关键词：
D O I：
10.1021/cr0502652
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The host-associated carbohydrate-mediated entry processes of HIV-1 are reviewed. Topics covered include the current HIV/AIDS treatments and limitations, HIV-1 surface protein Gp 120 and its role in the viral entry of CD4-positive T-cells vial fusion, polyanionics polysaccharides as anti-HIV agents in CD4-positive cells, and HIV surface protein gp120 and its role in the viral entry of CD4-negative cells.
引用
收藏
页码：1533 / 1552
页数：20
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