DBH deficiency in an elderly patient: efficacy and safety of chronic droxidopa

被引：3

作者：

Despas, Fabien ^{[1
,2
,3
,4
]}

Pathak, A. ^{[2
,3
,4
]}

Berry, M. ^{[5
]}

Cagnac, R. ^{[6
]}

Massabuau, P. ^{[5
]}

Liozon, E. ^{[7
]}

Galinier, M. ^{[5
]}

Senard, J. M. ^{[2
,3
,4
]}

机构：

[1] Fac Med Toulouse, Lab Pharmacol Clin, F-31000 Toulouse, France

[2] INSERM, Equipe 8, U858, F-31432 Toulouse, France

[3] Univ Toulouse, UPS, Inst Med Mol Rangueil, F-31432 Toulouse, France

[4] CHU Toulouse, Dept Clin Pharmacol, F-31432 Toulouse, France

[5] CHU Toulouse, Dept Cardiol, F-31432 Toulouse, France

[6] CHU Toulouse, Dept Nucl Med, F-31432 Toulouse, France

[7] CHU Dupuytren, Dept Internal Med, F-87000 Limoges, France

来源：

CLINICAL AUTONOMIC RESEARCH | 2010年 / 20卷 / 03期

关键词：

Dopamine beta-hydroxylase; Droxidopa; Orthostatic hypotension; Elderly; BETA-HYDROXYLASE DEFICIENCY; PRECURSOR THERAPY;

D O I：

10.1007/s10286-009-0049-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe the effects of chronic droxidopa in a patient with Dopamine beta-hydroxylase deficiency diagnosed at the age of 73. Investigations were performed to assess sympathetic activity (MIBG scintigraphy, catecholamines) and cardiovascular droxidopa safety.

引用

页码：205 / 207

页数：3

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