Interdisciplinary care programme to improve self-management for cancer patients undergoing stem cell transplantation: a prospective non-randomised intervention study

被引：9

作者：

Schmidt, H. ^{[1
,2
]}

Boese, S. ^{[1
,2
]}

Bauer, A. ^{[1
,2
]}

Landenberger, M.

Lau, A. ^{[3
]}

Stoll, O. ^{[4
]}

Schmoll, H. -J. ^{[5
]}

Mauz-Koerholz, C. ^{[6
]}

Kuss, O. ^{[7
,8
,9
]}

Jahn, P. ^{[10
,11
]}

机构：

[1] Martin Luther Univ Halle Wittenberg, Inst Hlth & Nursing Sci, Fac Med, Magdeburger Str 8, D-06097 Halle, Saale, Germany

[2] Martin Luther Univ Halle Wittenberg, Inst Hlth & Nursing Sci, Fac Med, Hlth & Nursing Sci, Halle, Saale, Germany

[3] Martin Luther Univ Halle Wittenberg, Inst Commun Media & Sports, Dept Sports Sci, Sports Sci, Halle, Germany

[4] Martin Luther Univ Halle Wittenberg, Inst Commun Media & Sports, Dept Sports Sci, Halle, Germany

[5] Martin Luther Univ Halle Wittenberg, Univ Hosp Halle, Dept Hematol & Onkol, Internal Med 4, Halle, Saale, Germany

[6] Martin Luther Univ Halle Wittenberg, Univ Hosp Halle, Dept Childrens Oncol, Halle, Saale, Germany

[7] Heinrich Heine Univ, Ctr Hlth & Soc, Fac Med, Inst Biometry & Epidemiol, Dusseldorf, Germany

[8] Heinrich Heine Univ Dusseldorf, Leibniz Inst Diabet Res, German Diabet Ctr, Inst Epidemiol & Biometry, Dusseldorf, Germany

[9] Martin Luther Univ Halle Wittenberg, Inst Med Epidemiol Biostat & Informat, Fac Med, Halle, Saale, Germany

[10] Martin Luther Univ Halle Wittenberg, Inst Hlth & Nursing Sci, Fac Med, Nursing Res,Univ Hosp, Halle, Saale, Germany

[11] Martin Luther Univ Halle Wittenberg, Univ Hosp Halle, Halle, Saale, Germany

来源：

EUROPEAN JOURNAL OF CANCER CARE | 2017年 / 26卷 / 04期

关键词：

stem cell transplantation; health-related quality of life; self-management; physical activation; mucositis; QUALITY-OF-LIFE; SUBJECTIVE GLOBAL ASSESSMENT; SKELETAL-MUSCLE STRENGTH; ORAL MUCOSITIS; PHYSICAL PERFORMANCE; AEROBIC EXERCISE; EUROPEAN-ORGANIZATION; NURSING INTERVENTION; DAILY QUESTIONNAIRE; NUTRITIONAL-STATUS;

D O I：

10.1111/ecc.12458

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The purpose of this single-centre prospective non-randomised study was to evaluate the effectiveness of an interdisciplinary care programme to enhance self-management in patients with haematopoietic stem cell transplantation (HSCT). Patients undergoing HSCT, aged >14years with informed consent were recruited (n=79). Patients in the intervention group (IG) received standard care plus the SCION-HSCT intervention to counteract three problems after HSCT: muscle weakness, oral mucositis and malnutrition. Control group patients received standard care. Primary endpoint was global health-related quality of life (HRQoL) at discharge (EORTC QLQ C30 v. 3.0). Baseline characteristics were balanced between both groups, except physical performance (ECOG) being significantly lower for patients of the IG. At discharge, no group differences could be seen regarding HRQoL. Non-confirmatory post hoc analyses showed for patients of the IG a shorter duration of hospitalisation (MD -10.90; 95% CI -18.05 to -3.75) and increased activity during hospitalisation (MD 2.44; 95% CI 1.27-3.61). In conclusion, clinical effectiveness of the intervention could not be proven with respect to the aspired improvement of HRQoL. However, the nurse-led interdisciplinary caring programme could be carried out in every day ward routine. Further research should focus on working mechanisms of complex interventions aiming to improve HRQoL of patients undergoing HSCT.

引用

页数：13

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