Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019-United States, January 2020-February 2020

被引:39
作者
Patel, Monita R. [1 ]
Carroll, Darin [1 ]
Ussery, Emily [1 ]
Whitham, Hilary [1 ]
Elkins, Christopher A. [1 ]
Noble-Wang, Judith [1 ]
Rasheed, James Kamile [1 ]
Lu, Xiaoyan [1 ]
Lindstrom, Stephen [1 ]
Bowen, Virginia [1 ]
Waller, Jessica [1 ]
Armstrong, Gregory [1 ]
Gerber, Susan [1 ]
Brooks, John T. [1 ]
机构
[1] Ctr Dis Control & Prevent, COVID 19 Response Team, Atlanta, GA USA
关键词
coronavirus; nasopharyngeal; oropharyngcal; testing; SARS-CoV-2;
D O I
10.1093/cid/ciaa759
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected <= 7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. However, NP swab cycle threshold values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect the amount of SARS-CoV-2.
引用
收藏
页码:482 / 485
页数:4
相关论文
共 7 条
[1]  
Centers for Disease Control and Prevention, 2020, INT GUID COLL HANDL
[2]  
Centers for Disease Control and Prevention, 2020, CDC 2019 NCOV REAL T
[3]  
Hanson KE, GUIDELINES DIAGNOSIS
[4]   Comparison of Nasopharyngeal and Oropharyngeal Swabs for the Diagnosis of Eight Respiratory Viruses by Real-Time Reverse Transcription-PCR Assays [J].
Kim, Curi ;
Ahmed, Jamal A. ;
Eidex, Rachel B. ;
Nyoka, Raymond ;
Waiboci, Lilian W. ;
Erdman, Dean ;
Tepo, Adan ;
Mahamud, Abdirahman S. ;
Kabura, Wamburu ;
Nguhi, Margaret ;
Muthoka, Philip ;
Burton, Wagacha ;
Breiman, Robert F. ;
Njenga, M. Kariuki ;
Katz, Mark A. .
PLOS ONE, 2011, 6 (06)
[5]   Identification of Respiratory Viruses in Adults: Nasopharyngeal versus Oropharyngeal Sampling [J].
Lieberman, David ;
Lieberman, Devora ;
Shimoni, Avi ;
Keren-Naus, Ayelet ;
Steinberg, Rachel ;
Shemer-Avni, Yonat .
JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (11) :3439-3443
[6]  
Wolf RC, 2020, NEUROPSYCHOBIOLOGY, V79, P335, DOI [10.1038/s41586-020-2984-3, 10.1159/000505601]
[7]  
Zou LR, 2020, NEW ENGL J MED, V382, P1177, DOI [10.1056/NEJMc2001737, 10.1148/radiol.2020200463]