Clinical Reasoning: Stepwise paralysis in a patient with adenocarcinoma of lung

被引：2

作者：

Furlan, Julio C. ^{[1
,2
,3
]}

Robinson, Lawrence R. ^{[2
,4
]}

Murray, Brian J. ^{[1
,5
]}

机构：

[1] Univ Toronto, Div Neurol, Toronto, ON M5S 1A1, Canada

[2] Univ Toronto, Div Phys Med & Rehabil, Toronto, ON M5S 1A1, Canada

[3] Univ Hlth Network, Toronto Rehabil Inst, Lyndhurst Ctr, Toronto, ON, Canada

[4] Univ Toronto, Sunnybrook Hlth Sci Ctr, Div Phys Med & Rehabil, Toronto, ON M5S 1A1, Canada

[5] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Med, Div Neurol, Toronto, ON M5S 1A1, Canada

来源：

NEUROLOGY | 2016年 / 86卷 / 12期

关键词：

GUILLAIN-BARRE-SYNDROME; SPINAL-CORD COMPRESSION; CANCER;

D O I：

10.1212/WNL.0000000000002496

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 54-year-old man presented with pain in the left chest for 3 days. His medical history was remarkable for hyperlipidemia managed with diet and statin. He denied tobacco smoking and consumption of alcohol. Physical examination was unrevealing. The patient was diagnosed with an adenocarcinoma of the lung harboring an epidermal growth factor receptor (EGFR) mutation that metastasized to T2-T4 levels. He was treated with radiotherapy and dexamethasone followed by Gefitinib.

引用

页码：E122 / E127

页数：6

共 17 条

[1]

Didelot Adrien, 2014, Handb Clin Neurol, V121, P1159, DOI 10.1016/B978-0-7020-4088-7.00078-X

[2]

Espay Alberto J, 2014, Handb Clin Neurol, V119, P365, DOI 10.1016/B978-0-7020-4086-3.00023-0

[3] Guillain-Barre syndrome as an initial manifestation of small cell lung carcinoma [J].

Ferrufino, Eddy ;

Camarasa, Ana ;

Chiner, Eusebi .

ARCHIVOS DE BRONCONEUMOLOGIA, 2011, 47 (02) :107-108

[4] Autonomic dysreflexia: A clinical emergency [J].

Furlan, Julio C. .

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2013, 75 (03) :496-500

[5] The combined use of surgery and radiotherapy to treat patients with epidural cord compression due to metastatic disease: a cost-utility analysis [J].

Furlan, Julio C. ;

Chan, Kelvin K. -W. ;

Sandoval, Guillermo A. ;

Lam, Kenneth C. K. ;

Klinger, Christopher A. ;

Patchell, Roy A. ;

Laporte, Audrey ;

Fehlings, Michael G. .

NEURO-ONCOLOGY, 2012, 14 (05) :631-640

[6] Cardiovascular complications after acute spinal cord injury: pathophysiology, diagnosis, and management [J].

Furlan, Julio C. ;

Fehlings, Michael G. .

NEUROSURGICAL FOCUS, 2008, 25 (05)

[7] Paraneoplastic Neurologic Syndrome in the PNS Euronetwork Database A European Study From 20 Centers [J].

Giometto, Bruno ;

Grisold, Wolfgang ;

Vitaliani, Roberta ;

Graus, Francesc ;

Honnorat, Jerome ;

Bertolini, Guido .

ARCHIVES OF NEUROLOGY, 2010, 67 (03) :330-335

[8]

Koike H, 2013, HAND CLINIC, V115, P713, DOI 10.1016/B978-0-444-52902-2.00041-2

[9] Paraneoplastic neurological syndromes [J].

Leypoldt, F. ;

Wandinger, K. -P. .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2014, 175 (03) :336-348

[10] A population-based study of malignant spinal cord compression in Ontario [J].

Loblaw, DA ;

Laperriere, NJ ;

Mackillop, WJ .

CLINICAL ONCOLOGY, 2003, 15 (04) :211-217

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