Acute on chronic liver failure

被引：14

作者：

Escorsell Manosa, Angels ^{[1
]}

Mas Ordeig, Antoni ^{[1
]}

机构：

[1] Univ Barcelona, IDIBAPS, CIBERehd,UCI, Inst Malalties Digest & Metabol,Hosp Clin, Barcelona, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2010年 / 33卷 / 02期

关键词：

Chronic liver disease; Hepatic encephalopathy; Liver transplantation; Hepatorenal syndrome; EXTRACORPOREAL ALBUMIN DIALYSIS; HEPATIC-ENCEPHALOPATHY; HEPATORENAL-SYNDROME; SYSTEMIC HEMODYNAMICS; RECIRCULATING SYSTEM; CLINICAL-EXPERIENCE; CIRRHOSIS; PROMETHEUS; SUPPORT; MARS;

D O I：

10.1016/j.gastrohep.2009.10.003

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Acute-on-Chronic Liver Failure (ACLF) is a recently introduced term defined as severe acute deterioration of an established liver disease. This entity usually develops after an acute insult. The main clinical manifestations are hepatorenal syndrome, hepatic encephalopathy and organ failure, with a high risk of death in the short term. The true incidence of ACLF remains difficult to determine due to confusions surrounding the definition of this entity, but seems to be 40% at 5 years in patients with advanced cirrhosis, which translates into 4,000 cases in Europe within this time span. The treatment of choice is liver transplantation. However, due to the shortage of suitable organs and morbidity and mortality in these patients, other options must be used. (C) 2009 Elsevier Espana, S.L All rights reserved.

引用

页码：126 / 134

页数：9

共 35 条

[1] Hyponatremia in cirrhosis:: Results of a patient population survey [J].