A report of haploidentical allogeneic haematopoietic stem cell transplantation for inherited bone marrow failure in Sri Lanka

被引：0

作者：

Wickramasinghe, Wasanthi ^{[1
]}

Raj, Revathi ^{[2
]}

Goonatillake, Shama ^{[3
]}

Abayadeera, Anuja ^{[1
]}

Samarasinghe, Malik ^{[1
]}

Galhenage, Jeewaka ^{[4
]}

Aarewatte, Pavithra ^{[5
]}

Mendis, Devan ^{[5
]}

Thevarapperuma, Chandima ^{[5
]}

Dissanayake, Ruwangi ^{[1
]}

Gooneratne, Lallindra ^{[1
]}

机构：

[1] Univ Colombo, Fac Med, Colombo, Sri Lanka

[2] Apollo Children Hosp, Chennai, Tamil Nadu, India

[3] Asiri Surg Hosp, Colombo, Sri Lanka

[4] Natl Blood Transfus Serv, Colombo, Sri Lanka

[5] Lady Ridgeway Hosp Children, Colombo, Sri Lanka

来源：

CEYLON MEDICAL JOURNAL | 2022年 / 67卷 / 01期

关键词：

CYTOKINE-RELEASE SYNDROME; BLOOD;

D O I：

10.4038/cmj.v67i1.9554

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bone marrow failure (BMF) in children can be idiopathic (70-80%) or inherited. Haematopoietic stem cell transplantation (HSCT) is the only cure for both causes. Allogeneic HSCT requires a suitable donor. Many children will not have a HLA matched sibling or unrelated donor. A haploidentical donor is available for all children as each parent will have at minimum a 50% HLA match. This report of a 7-year old girl with BMF treated with a haplo-HSCT, the first in Sri Lanka, highlights the importance of developing a haploidentical HSCT programme as a potential cure for a disease with a dismal outcome.

引用

页码：17 / 19

页数：3

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