A report of haploidentical allogeneic haematopoietic stem cell transplantation for inherited bone marrow failure in Sri Lanka

被引：0
|
作者：
Wickramasinghe, Wasanthi [1 ]
Raj, Revathi [2 ]
Goonatillake, Shama [3 ]
Abayadeera, Anuja [1 ]
Samarasinghe, Malik [1 ]
Galhenage, Jeewaka [4 ]
Aarewatte, Pavithra [5 ]
Mendis, Devan [5 ]
Thevarapperuma, Chandima [5 ]
Dissanayake, Ruwangi [1 ]
Gooneratne, Lallindra [1 ]
机构：
[1] Univ Colombo, Fac Med, Colombo, Sri Lanka
[2] Apollo Children Hosp, Chennai, Tamil Nadu, India
[3] Asiri Surg Hosp, Colombo, Sri Lanka
[4] Natl Blood Transfus Serv, Colombo, Sri Lanka
[5] Lady Ridgeway Hosp Children, Colombo, Sri Lanka
来源：
CEYLON MEDICAL JOURNAL | 2022年 / 67卷 / 01期
关键词：
CYTOKINE-RELEASE SYNDROME; BLOOD;
D O I：
10.4038/cmj.v67i1.9554
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Bone marrow failure (BMF) in children can be idiopathic (70-80%) or inherited. Haematopoietic stem cell transplantation (HSCT) is the only cure for both causes. Allogeneic HSCT requires a suitable donor. Many children will not have a HLA matched sibling or unrelated donor. A haploidentical donor is available for all children as each parent will have at minimum a 50% HLA match. This report of a 7-year old girl with BMF treated with a haplo-HSCT, the first in Sri Lanka, highlights the importance of developing a haploidentical HSCT programme as a potential cure for a disease with a dismal outcome.
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收藏
页码：17 / 19
页数：3
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