Resolution of echocardiographic features of left ventricular non-compaction and systolic dysfunction following treatment for heart failure

Isolated left ventricular non-compaction (IVNC) is a myocardial disease, thought to be related to abnormal embryological development of the myocardium. The condition may be associated with left ventricular dysfunction and heart failure, as well as arrhythmias and thrombo-embolism. The left ventricular dysfunction is generally regarded to be progressive in nature, leading to worsening heart failure and death. We report a case in which initial investigations fulfilled the diagnostic criteria for IVNC. However, follow-up investigation demonstrated recovery of left ventricular systolic function as well as resolution of the features of non-compaction, making a retrospective diagnosis of myocarditis more likely.