Obesity, Chronic Kidney Disease, and Kidney Transplantation: An Evolving Relationship

被引：15

作者：

Azhar, Ambreen ^{[1
,2
]}

Hassan, Nabeel ^{[3
]}

Tapolyai, Mihaly ^{[4
]}

Molnar, Miklos Z. ^{[1
,5
,6
]}

机构：

[1] Methodist Univ Hosp, James D Eason Transplant Inst, Memphis, TN USA

[2] Univ Tennessee, Hlth Sci Ctr, Dept Surg, Memphis, TN USA

[3] Methodist Univ Hosp, Memphis, TN USA

[4] VA Med Ctr, Div Nephrol, Memphis, TN USA

[5] Univ Tennessee, Dept Med, Div Nephrol, Hlth Sci Ctr, Memphis, TN 38104 USA

[6] Semmelweis Univ, Dept Transplantat & Surg, Budapest, Hungary

来源：

SEMINARS IN NEPHROLOGY | 2021年 / 41卷 / 02期

关键词：

Obesity paradox; obesity and kidney disease; kidney transplant in obese patients; reverse heat map of obesity; BODY-MASS INDEX; STAGE RENAL-DISEASE; BARIATRIC SURGERY; WEIGHT-GAIN; REVERSE EPIDEMIOLOGY; PHYSICAL-ACTIVITY; HEALTHY OBESITY; ESTIMATED GFR; RISK-FACTORS; PARADOX;

D O I：

10.1016/j.semnephrol.2021.03.013

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Obesity has a fundamental role in driving the global kidney disease burden. The perplexing relationship of obesity with chronic kidney disease remains debated. However, a thorough understanding of the interplay of obesity in conjunction with chronic kidney disease and appropriate management options is lacking, leading to further increases in morbidity and mortality. Moreover, underutilization of bariatric procedures and unrealistic expectations of weight reduction based on body mass index, leading to poor access to kidney transplantation, are fueling the fire. In this review, we summarize the available data related to the obesity and chronic kidney disease association and its novel management options. (C) 2021 Elsevier Inc. All rights reserved.

引用

页码：189 / 200

页数：12

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