Continuous positive airway pressure for obstructive sleep apnea

被引:88
作者
Basner, Robert C. [1 ]
机构
[1] Columbia Univ Coll Phys & Surg, Div Pulm Allergy & Crit Care, New York, NY 10032 USA
关键词
D O I
10.1056/NEJMct066953
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
During an evaluation by his internist, a 48-year-old man reports that his wife tells him that he snores loudly. Further questioning reveals that he has been falling asleep whenever sedentary. His physical examination is notable for truncal obesity (body-mass index [ the weight in kilograms divided by the square of the height in meters], 32) and hypertension ( blood pressure, 150/96 mm Hg). He is referred to a sleep specialist for nocturnal polysomnography ( sleep study), which reveals evidence of obstructive sleep apnea, with an obstructive apnea - hypopnea index ( defined as the total number of episodes of obstructive apnea and hypopnea per hour of sleep) of 50, a nadir value for arterial oxygen saturation of 65%, and an arterial oxygen saturation below 90% during 19% of sleep time. Treatment with continuous positive airway pressure (CPAP) is recommended.
引用
收藏
页码:1751 / 1758
页数:8
相关论文
共 67 条
[1]   Metabolic syndrome in obstructive sleep apnea and related cardiovascular risk [J].
Ambrosetti, Marco ;
Lucioni, Anna Maria ;
Conti, Simonetta ;
Pedretti, Roberto F. E. ;
Neri, Marghenta .
JOURNAL OF CARDIOVASCULAR MEDICINE, 2006, 7 (11) :826-829
[2]   Cost-effectiveness of continuous positive airway pressure therapy for moderate to severe obstructive sleep apnea/hypopnea [J].
Ayas, Najib T. ;
FitzGerald, J. Mark ;
Fleetham, John A. ;
White, David P. ;
Schulzer, Michael ;
Ryan, C. Frank ;
Ghaeli, Reza ;
Mercer, G. William ;
Cooper, Peter ;
Tan, Michael C. Y. ;
Marra, Carlo A. .
ARCHIVES OF INTERNAL MEDICINE, 2006, 166 (09) :977-984
[3]   Auto-titrating versus standard continuous positive airway pressure for the treatment of obstructive sleep apnea: Results of a meta-analysis [J].
Ayas, NT ;
Patel, SR ;
Malhotra, A ;
Schulzer, M ;
Malhotra, M ;
Jung, D ;
Fleetham, J ;
White, DP .
SLEEP, 2004, 27 (02) :249-253
[4]   IMPAIRMENT OF CEREBRAL PERFUSION DURING OBSTRUCTIVE SLEEP APNEAS [J].
BALFORS, EM ;
FRANKLIN, KA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1994, 150 (06) :1587-1591
[5]   A Randomized controlled trial of continuous positive airway pressure in mild obstructive sleep apnea [J].
Barnes, M ;
Houston, D ;
Worsnop, CJ ;
Neill, AM ;
Mykytyn, IJ ;
Kay, A ;
Trinder, J ;
Saunders, NA ;
McEvoy, RD ;
Pierce, RJ .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (06) :773-780
[6]   SNORING AND SLEEP-APNEA - A POPULATION STUDY IN AUSTRALIAN MEN [J].
BEARPARK, H ;
ELLIOTT, L ;
GRUNSTEIN, R ;
CULLEN, S ;
SCHNEIDER, H ;
ALTHAUS, W ;
SULLIVAN, C .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1995, 151 (05) :1459-1465
[7]   Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea [J].
Becker, HF ;
Jerrentrup, A ;
Ploch, T ;
Grote, L ;
Penzel, T ;
Sullivan, CE ;
Peter, JH .
CIRCULATION, 2003, 107 (01) :68-73
[8]   Prevalence of sleep-disordered breathing in women - Effects of gender [J].
Bixler, EO ;
Vgontzas, AN ;
Lin, HM ;
Ten Have, T ;
Rein, J ;
Vela-Bueno, A ;
Kales, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (03) :608-613
[9]   An oral hypnotic medication does not improve continuous positive airway pressure compliance in men with obstructive sleep apnea [J].
Bradshaw, David A. ;
Ruff, Gregory A. ;
Murphy, David P. .
CHEST, 2006, 130 (05) :1369-1376
[10]   Mortality in obstructive sleep apnea-hypopnea patients treated with positive airway pressure [J].
Campos-Rodriguez, F ;
Peña-Griñan, N ;
Reyes-Nuñez, N ;
De la Cruz-Moron, I ;
Perez-Ronchel, J ;
De la Vega-Gallardo, F ;
Fernandez-Palacin, A .
CHEST, 2005, 128 (02) :624-633