Mitochondrial DNA inheritance in Saccharomyces cerevisiae

被引：77

作者：

Berger, KH ^{[1
]}

Yaffe, MP ^{[1
]}

机构：

[1] Univ Calif San Diego, Div Biol, Sect Cell & Dev Biol, La Jolla, CA 92093 USA

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 11期

关键词：

D O I：

10.1016/S0966-842X(00)01862-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Respiratory metabolism depends on mitochondrial DNA, yet the mechanisms that ensure the inheritance of the mitochondrial genome are largely obscure. Recent studies with Saccharomyces cerevisiae suggest that distinct factors mediate the active segregation of mitochondrial DNA during mitotic growth. The identification of the proteins required for the maintenance of the mitochondrial genome provides clues to the mechanisms of, and molecular machinery involved in, mitochondrial DNA inheritance.

引用

页码：508 / 513

页数：6

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