Rhodium(III)-Catalyzed Cyclative Capture Approach to Diverse 1-Aminoindoline Derivatives at Room Temperature

被引：135

作者：

Zhao, Dongbing ^{[1
]}

Vasquez-Cespedes, Suhelen ^{[1
]}

Glorius, Frank ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 05期

基金：

欧洲研究理事会;

关键词：

C-H functionalization; directing groups; heterocycles; indolines; rhodium; C-H ACTIVATION; UNSYMMETRICAL AZO-COMPOUNDS; BOND ACTIVATION; REGIOSELECTIVE SYNTHESIS; OXIDATIVE OLEFINATION; CINNOLINIUM SALTS; ARYLBORONIC ACIDS; INTERNAL ALKYNES; DIRECTING GROUP; FUNCTIONALIZATION;

D O I：

10.1002/anie.201410342

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Rh-III-catalyzed C-H activation/cyclative capture approach, involving a nucleophilic addition of C(sp(3))-Rh species to polarized double bonds is reported. This constitutes the first intermolecular catalytic method to directly access 1-aminoindolines with a broad substituent scope under mild conditions.

引用

页码：1657 / 1661

页数：5

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