Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis

被引：42

作者：

Ozgocmen, Salih ^{[1
]}

Ardicoglu, Ozge ^{[2
]}

Kamanli, Ayhan ^{[2
]}

Kaya, Arzu ^{[2
]}

Durmus, Bekir ^{[3
]}

Yildirim, Kadir ^{[4
]}

Baysal, Ozlem ^{[3
]}

Gur, Ali ^{[5
]}

Karatay, Saliha ^{[4
]}

Altay, Zuhal ^{[3
]}

Cevik, Remzi ^{[5
]}

Erdal, Akin ^{[4
]}

Ersoy, Yuksel ^{[3
]}

Sarac, Aysegul J. ^{[5
]}

Tekeoglu, Ibrahim ^{[6
]}

Ugur, Mahir ^{[4
]}

Nas, Kemal ^{[5
]}

Senel, Kazim ^{[4
]}

Ulusoy, Hasan ^{[2
]}

机构：

[1] Erciyes Univ, Dept Phys Med & Rehabil, Gevher Nesibe Hosp, Div Rheumatol,Sch Med, TR-38039 Kayseri, Turkey

[2] Firat Univ, Firat Univ Hosp, Dept Phys Med & Rehabil, Div Rheumatol,Fac Med, TR-23169 Elazig, Turkey

[3] Inonu Univ, Dept Phys Med & Rehabil, Fac Med, Malatya, Turkey

[4] Ataturk Univ, Dept Phys Med & Rehabil, Fac Med, Erzurum, Turkey

[5] Dicle Univ, Dept Phys Med & Rehabil, Fac Med, Diyarbakir, Turkey

[6] Yuzuncu Yil Univ, Div Rheumatol, Dept Phys Med & Rehabil, Fac Med, Van, Turkey

来源：

JOURNAL OF RHEUMATOLOGY | 2009年 / 36卷 / 12期

关键词：

ANKYLOSING SPONDYLITIS; JUVENILE ONSET; ADULT ONSET; DIAGNOSTIC DELAY; INDEX; BATH;

D O I：

10.3899/jrheum.090435

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective. To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design. Methods. A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey. Results. Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% Cl 1.25-6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51-6.98, adjusted for current age; and OR 2.26, 95% CI 1.07-4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life. Conclusion. JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient Populations. (First Release Nov 1 2009; J Rheumatol 2009;36:2830-3; doi: 10.3899/jrheum.090435)

引用

页码：2830 / 2833

页数：4

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