A ferrocene-based pseudopeptide chiroptical switch

被引：5

作者：

Opacak, Sasa ^{[1
]}

Babic, Darko ^{[1
]}

Peric, Berislav ^{[1
]}

Marinic, Zeljko ^{[1
]}

Smrecki, Vilko ^{[1
]}

Pem, Barbara ^{[2
]}

Vrcek, Ivana Vinkovic ^{[2
]}

Kirin, Srecko I. ^{[1
]}

机构：

[1] Rudjer Boskovic Inst, Bijenicka Cesta 54, HR-10000 Zagreb, Croatia

[2] Inst Med Res & Occupat Hlth, Ksaverska Cesta 2, HR-10000 Zagreb, Croatia

来源：

DALTON TRANSACTIONS | 2021年 / 50卷 / 13期

关键词：

CONFORMATIONAL-ANALYSIS; CIRCULAR-DICHROISM; CHIRALITY; INVERSION; HELICITY; DESIGN; LABILE; CHAINS;

D O I：

10.1039/d1dt00508a

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We present a double-stranded ferrocene pseudopeptide 2b which exhibits stimuli responsive chirality inversion triggered by solvent exchange or acid addition. Compound 2b exists as a mixture of self-assembled fast exchanging oligomers which macroscopically behave as a chiroptical switch with two stable states. The ferrocene group inversion results in a distinct CD signal in the visible part of the spectrum. The inversion is accomplished through a conformational change due to a rearrangement of hydrogen bonding forcing the rotation of ferrocene rings.

引用

页码：4504 / 4511

页数：8