A rapid, nearly quantitative conversion of codeine to hydrocodone

被引:7
作者
Black, TH [1 ]
Forsee, JC [1 ]
Probst, DA [1 ]
机构
[1] Eastern Illinois Univ, Dept Chem, Charleston, IL 61920 USA
关键词
D O I
10.1080/00397910008086930
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A very rapid, two-step, virtually quantitative synthesis of hydrocodone from codeine, via the intermediacy of dihydrocodeine, has been developed.
引用
收藏
页码:3195 / 3201
页数:7
相关论文
共 5 条
  • [1] *ALDR CHEM CO, 328650 ALDR CHEM CO
  • [2] RAPOPORT H., 1950, JOUR ORGANIC CHEM, V15, P1103, DOI 10.1021/jo01151a029
  • [3] *RES BIOCH INT, C122 RES BIOCH INT
  • [4] *RES BIOCH INT, H114 RES BIOCH INT
  • [5] About alkaloid hydration (reduction catalysis).
    Skita, A
    Franck, HH
    [J]. BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1911, 44 : 2862 - 2867