Diagnostic algorithm for Raynaud's phenomenon and vascular skin lesions in systemic lupus erythematosus

被引:10
|
作者
Richter, J. G. [2 ]
Sander, O. [2 ]
Schneider, M. [2 ]
Klein-Weigel, P. [1 ]
机构
[1] DRK Kliniken Berlin Kopenick, Dept Internal Med Angiol & Cardiovasc Rehabil, Berlin, Germany
[2] Univ Dusseldorf, Dept Endocrinol Diabet & Rheumatol, Dusseldorf, Germany
关键词
acrocyanosis; nailfold capillaroscopy; Raynaud's phenomenon; skin lesion; systemic lupus erythematosus; vasculitis; CONNECTIVE-TISSUE DISEASE; NAILFOLD CAPILLARY MICROSCOPY; ANTIPHOSPHOLIPID ANTIBODIES; ANTICARDIOLIPIN ANTIBODIES; CUTANEOUS MANIFESTATIONS; CLINICAL MANIFESTATIONS; RHEUMATIC-DISEASES; SLE PATIENTS; FOLLOW-UP; ABNORMALITIES;
D O I
10.1177/0961203310374304
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Skin discolorations and skin lesions due to vascular pathologies are common clinical features in systemic lupus erythematosus. A variety of clinical manifestations such as Raynaud's phenomenon, acrocyanosis, livedo patterns, erythematous or violaceous macules and papules or necrosis are triggered by heterogeneous pathophysiological mechanisms such as vasospasm, vasculitis or thromboembolism. A standardized macro-and microvascular assessment is necessary to establish the correct diagnosis. We describe and illustrate common clinical features of vascular skin manifestations in systemic lupus erythematosus and present a diagnostic algorithm. Lupus (2010) 19, 1087-1095.
引用
收藏
页码:1087 / 1095
页数:9
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