Dupuytren's contracture and handwork: A case-control study

被引：11

作者：

Haines, Alfred ^{[1
,2
]}

Levis, Carolyn ^{[3
]}

Goldsmith, Charles H. ^{[1
,4
,5
]}

Kaur, Manraj ^{[3
,4
]}

Duku, Eric ^{[6
]}

Wells, Richard ^{[7
,8
]}

Walter, Stephen D. ^{[1
,9
]}

Rook, Cheryl ^{[10
]}

Stock, Susan ^{[11
]}

Liss, Gary ^{[12
,13
]}

Murphy, Jessica ^{[3
,4
]}

Thoma, Achilleas ^{[1
,3
,4
]}

机构：

[1] McMaster Univ, Dept Clin Epidemiol & Biostat, Suite 101,206 James St South, Hamilton, ON L8P 3A9, Canada

[2] McMaster Univ, Dept Family Med, Hamilton, ON, Canada

[3] McMaster Univ, Dept Surg, Hamilton, ON, Canada

[4] McMaster Univ, Surg Outcomes Res Ctr SOURCE, Hamilton, ON, Canada

[5] Simon Fraser Univ, Fac Hlth Sci, Burnaby, BC, Canada

[6] Hamilton Hlth Sci, Offord Ctr Child Studies, Chedoke Site, Hamilton, ON, Canada

[7] Univ Waterloo, Fac Appl Hlth Sci, Dept Kinesiol, Waterloo, ON, Canada

[8] Inst Work & Hlth, Toronto, ON, Canada

[9] McMaster Univ, Dept Math & Stat, Hamilton, ON, Canada

[10] Occupat Hlth Clin Ontario Workers Inc, Toronto, ON, Canada

[11] Univ Montreal, Dept Social & Prevent Med, Res Ctr CR CHUM, Montreal, PQ, Canada

[12] Univ Toronto, Gage Occupat & Environm Hlth Unit, Toronto, ON, Canada

[13] Ontario Minist Labor, Toronto, ON, Canada

来源：

AMERICAN JOURNAL OF INDUSTRIAL MEDICINE | 2017年 / 60卷 / 08期

关键词：

Dupuytren's contracture; frequency-weighted; heavy handwork; repetitive handwork; vibration exposure; OCCUPATIONAL-EXPOSURE; CAGE QUESTIONNAIRE; DISEASE; WORK; VIBRATION; ALCOHOL; DISORDERS;

D O I：

10.1002/ajim.22736

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. Methods: Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of work were weighted by average "frequency," for RHW, and average "intensity," for HHW and use of vibrating tool. Logistic regression was used to evaluate risk of developing DC associated with the above-mentioned factors. Results: Data from 129 cases (74 clinical, 106 controls) was analyzed. Family history, male gender and age (decades) were associated with increased risk of DC. Results indicate that the risk becomes substantial after about 30 years of steady RHW. Independent effects of intensity-weighted HHW and vibrating exposure were not established. Conclusions: Frequency-weighted RHW increases DC risk. Additionally, a strong association between DC, male gender and heredity was found.

引用

页码：724 / 733

页数：10

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