EFFECT OF FREQUENCY-DEPENDENT ATTENUATION ON PREDICTED HISTOTRIPSY WAVEFORMS IN TISSUE-MIMICKING PHANTOMS

被引：23
|
作者：
Bader, Kenneth B. [1 ]
Crowe, Michael J. [2 ]
Raymond, Jason L. [2 ]
Holland, Christy K. [1 ,2 ]
机构：
[1] Univ Cincinnati, Dept Internal Med, Div Cardiovasc Hlth & Dis, Cincinnati, OH USA
[2] Univ Cincinnati, Biomed Engn Program, Cincinnati, OH USA
来源：
ULTRASOUND IN MEDICINE AND BIOLOGY | 2016年 / 42卷 / 07期
基金：
美国国家卫生研究院;
关键词：
Histotripsy; Shock waves; Ultrasonic attenuation; Acoustical properties; Cavitation; THERAPEUTIC ULTRASOUND FIELDS; EROSION; LIVER;
D O I：
10.1016/j.ultrasmedbio.2016.02.010
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Tissue-mimicking phantoms are employed for the assessment of shocked histotripsy pulses in vitro. These broadband shock waves are critical for tissue ablation and are influenced by the frequency-dependent attenuation of the medium. The density, sound speed and attenuation spectra (2-25 MHz) were measured for phantoms that mimic key histotripsy targets. The influence of non-linear propagation relative to the attenuation was described in terms of Gol'dberg number. An expression was derived to estimate the bandwidth of shocked histotripsy pulses for power law-dependent attenuation. The expression is independent of the fundamental frequency of the histotripsy pulse for linear frequency-dependent attenuation. (E-mail: christy.holland@uc.edu) (C) 2016 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码：1701 / 1705
页数：5
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