Response to Trametinib of a Pulmonary Langerhans Cell Histiocytosis Harboring a MAP2K1 Deletion

被引:27
作者
Lorillon, Gwenael [1 ]
Jouenne, Fanelie [1 ,2 ]
Baroudjian, Barouyr [1 ]
de Margerie-Mellon, Constance [1 ,2 ]
Vercellino, Laetitia [1 ]
Meignin, Veronique [1 ,3 ]
Lebbe, Celeste [1 ,2 ,4 ]
Vassallo, Robert [5 ]
Mourah, Samia [1 ,2 ,4 ]
Tazi, Abdellatif [1 ,2 ,6 ]
机构
[1] AP HP, Paris, France
[2] Univ Paris Diderot, Paris, France
[3] INSERM, UMR S1165, Paris, France
[4] INSERM, U976, Paris, France
[5] Mayo Clin, Rochester, MN USA
[6] CRESS, U1153, Paris, France
关键词
ERDHEIM-CHESTER DISEASE; MUTATIONS; VEMURAFENIB; ACTIVATION;
D O I
10.1164/rccm.201802-0275LE
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:675 / 678
页数:4
相关论文
共 11 条
[1]   Targeted therapies in 54 patients with Erdheim-Chester disease, including follow-up after interruption (the LOVE study) [J].
Aubart, Fleur Cohen ;
Emile, Jean-Francois ;
Carrat, Fabrice ;
Charlotte, Frederic ;
Benameur, Neila ;
Donadieu, Jean ;
Maksud, Philippe ;
Idbaih, Ahmed ;
Barete, Stephane ;
Hoang-Xuan, Khe ;
Amoura, Zahir ;
Haroche, Julien .
BLOOD, 2017, 130 (11) :1377-1380
[2]   Recurrent BRAF mutations in Langerhans cell histiocytosis [J].
Badalian-Very, Gayane ;
Vergilio, Jo-Anne ;
Degar, Barbara A. ;
MacConaill, Laura E. ;
Brandner, Barbara ;
Calicchio, Monica L. ;
Kuo, Frank C. ;
Ligon, Azra H. ;
Stevenson, Kristen E. ;
Kehoe, Sarah M. ;
Garraway, Levi A. ;
Hahn, William C. ;
Meyerson, Matthew ;
Fleming, Mark D. ;
Rollins, Barrett J. .
BLOOD, 2010, 116 (11) :1919-1923
[3]   Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis [J].
Chakraborty, Rikhia ;
Burke, Thomas M. ;
Hampton, Oliver A. ;
Zinn, Daniel J. ;
Lim, Karen Phaik Har ;
Abhyankar, Harshal ;
Scull, Brooks ;
Kumar, Vijetha ;
Kakkar, Nipun ;
Wheeler, David A. ;
Roy, Angshumoy ;
Poulikakos, Poulikos I. ;
Merad, Miriam ;
McClain, Kenneth L. ;
Parsons, D. Williams ;
Allen, Carl E. .
BLOOD, 2016, 128 (21) :2533-2537
[4]   Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis [J].
Chakraborty, Rikhia ;
Hampton, Oliver A. ;
Shen, Xiaoyun ;
Simko, Stephen J. ;
Shih, Albert ;
Abhyankar, Harshal ;
Lim, Karen Phaik Har ;
Covington, Kyle R. ;
Trevino, Lisa ;
Dewal, Ninad ;
Muzny, Donna M. ;
Doddapaneni, Harshavardhan ;
Hu, Jianhong ;
Wang, Linghua ;
Lupo, Philip J. ;
Hicks, M. John ;
Bonilla, Diana L. ;
Dwyer, Karen C. ;
Berres, Marie-Luise ;
Poulikakos, Poulikos I. ;
Merad, Miriam ;
McClain, Kenneth L. ;
Wheeler, David A. ;
Allen, Carl E. ;
Parsons, D. Williams .
BLOOD, 2014, 124 (19) :3007-3015
[5]   Vemurafenib for BRAF V600-Mutant Erdheim-Chester Disease and Langerhans Cell Histiocytosis Analysis of Data From the Histology-Independent, Phase 2, Open-label VE-BASKET Study [J].
Diamond, Eli L. ;
Subbiah, Vivek ;
Lockhart, A. Craig ;
Blay, Jean-Yves ;
Puzanov, Igor ;
Chau, Ian ;
Raje, Noopur S. ;
Wolf, Jurgen ;
Erinjeri, Joseph P. ;
Torrisi, Jean ;
Lacouture, Mario ;
Elez, Elena ;
Martinez-Valle, Ferran ;
Durham, Benjamin ;
Arcila, Maria E. ;
Ulaner, Gary ;
Abdel-Wahab, Omar ;
Pitcher, Bethany ;
Makrutzki, Martina ;
Riehl, Todd ;
Baselga, Jose ;
Hyman, David M. .
JAMA ONCOLOGY, 2018, 4 (03) :384-388
[6]   Reproducible and Sustained Efficacy of Targeted Therapy With Vemurafenib in Patients With BRAFV600E-Mutated Erdheim-Chester Disease [J].
Haroche, Julien ;
Cohen-Aubart, Fleur ;
Emile, Jean-Francois ;
Maksud, Philippe ;
Drier, Aurelie ;
Toledano, Dan ;
Barete, Stephane ;
Charlotte, Frederic ;
Cluzel, Philippe ;
Donadieu, Jean ;
Benameur, Neila ;
Grenier, Philippe A. ;
Besnard, Sophie ;
Ory, Jean-Paul ;
Lifermann, Francois ;
Idbaih, Ahmed ;
Granel, Brigitte ;
Graffin, Bruno ;
Hervier, Baptiste ;
Arnaud, Laurent ;
Amoura, Zahir .
JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (05) :411-U52
[7]   Mutually exclusive extracellular signal-regulated kinase pathway mutations are present in different stages of multi-focal pulmonary Langerhans cell histiocytosis supporting clonal nature of the disease [J].
Kamionek, Michal ;
Moghaddam, Parnian Ahmadi ;
Sakhdari, Ali ;
Kovach, Alexandra E. ;
Welch, Matthew ;
Meng, Xiuling ;
Dresser, Karen ;
Tomaszewicz, Keith ;
Cosar, Ediz F. ;
Mark, Eugene J. ;
Fraire, Armando E. ;
Hutchinson, Lloyd .
HISTOPATHOLOGY, 2016, 69 (03) :499-509
[8]   Real-time genomic profiling of histiocytoses identifies early-kinase domain BRAF alterations while improving treatment outcomes [J].
Lee, Lynn H. ;
Gasilina, Anjelika ;
Roychoudhury, Jayeeta ;
McCormack, Francis X. ;
Pressey, Joseph ;
Grimley, Michael S. ;
Lorsbach, Robert ;
Ali, Siraj ;
Bailey, Mark ;
Stephens, Philip ;
Ross, Jeffrey S. ;
Miller, Vincent A. ;
Nassar, Nicolas N. ;
Kumar, Ashish R. .
JCI INSIGHT, 2017, 2 (03)
[9]   Cladribine Is Effective against Cystic Pulmonary Langerhans Cell Histiocytosis [J].
Lorillon, Gwenael ;
Bergeron, Anne ;
Detourmignies, Laurence ;
Jouneau, Stephane ;
Wallaert, Benoit ;
Frija, Jacques ;
Tazi, Abdellatif .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2012, 186 (09) :930-932
[10]   Recurrent NRAS mutations in pulmonary Langerhans cell histiocytosis [J].
Mourah, Samia ;
How-Kit, Alexandre ;
Meignin, Veronique ;
Gossot, Dominique ;
Lorillon, Gwenael ;
Bugnet, Emmanuelle ;
Mauger, Florence ;
Lebbe, Celeste ;
Chevret, Sylvie ;
Tost, Joerg ;
Tazi, Abdellatif .
EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (06) :1785-1796