Advances in the research of plant-derived natural products against retinoblastoma

被引：1

作者：

Liu, Jing-Chen ^{[1
,2
,3
]}

Zhang, Chun-Li ^{[4
]}

Dong, Kai-Ye ^{[5
]}

Li, Ming-Jun ^{[2
]}

Sun, Shu-Guang ^{[2
,6
]}

Li, Cai-Rui ^{[2
,5
]}

机构：

[1] Jiangxi Univ Tradit Chinese Med, Jiangxi Prov Hosp Integrated Tradit Chinese & Wes, Dept Ophthalmol, Affiliated Hosp 4, Nanchang 330003, Jiangxi, Peoples R China

[2] Dali Univ, Sch Clin Med, 22 Wanhua Rd, Dali 671000, Yunnan, Peoples R China

[3] Jiangxi Univ Tradit Chinese Med, Sch Clin Med, Nanchang 330006, Jiangxi, Peoples R China

[4] Gen Hosp Southern Theatre Command, Dept Ophthalmol, Guangzhou 510010, Guangdong, Peoples R China

[5] Dali Univ, Dept Ophthalmol, Affiliated Hosp 1, Dali 671000, Yunnan, Peoples R China

[6] Dali Univ, Dept Endocrinol, Affiliated Hosp 1, Dali 671000, Yunnan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY | 2022年 / 15卷 / 08期

关键词：

plant-derived; retinoblastoma; apoptosis; cell cycle; drug resistance; CELL-CYCLE ARREST; NF-KAPPA-B; DRUG-RESISTANCE; CANCER; INHIBITION; AUTOPHAGY; ANGIOGENESIS; EXPRESSION; APOPTOSIS; PROTEINS;

D O I：

10.18240/ijo.2022.08.24

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and medical constraints, many children receive treatment only in the metaphase and advanced clinical stages, resulting in high rates of blindness and disability. Although several approaches exist in the treatment of RB, some children with the disease do not have satisfactory results because of various factors. Plant-derived natural products have shown definite therapeutic effects in the treatment of various tumors and are also widely used in the study of RB. We review plant-derived natural products used in the study of anti-RB to provide ideas for the clinical application of these drugs and the development of new therapeutic drugs.

引用

页码：1391 / 1400

页数：10

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