Receptor-interacting protein (RIP) kinase family

被引：148
作者：
Zhang, Duanwu [1 ]
Lin, Juan [1 ]
Han, Jiahuai [1 ]
机构：
[1] Xiamen Univ, Sch Life Sci, Minist Educ Cell Biol & Tumor Cell Engn, Key Lab, Xiamen 361005, Peoples R China
来源：
CELLULAR & MOLECULAR IMMUNOLOGY | 2010年 / 7卷 / 04期
关键词：
apoptosis; kinase; necrosis; RIP; TNF; NF-KAPPA-B; NECROSIS-FACTOR RECEPTOR; C-ASSOCIATED KINASE; INDUCED CELL-DEATH; PARKINSONS-DISEASE; ADAPTER MOLECULE; IMMUNE-RESPONSES; MICE LACKING; TNF-ALPHA; IKK-ALPHA;
D O I：
10.1038/cmi.2010.10
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Receptor-interacting protein (RIP) kinases are a group of threonine/serine protein kinases with a relatively conserved kinase domain but distinct non-kinase regions. A number of different domain structures, such as death and caspase activation and recruitment domain (CARD) domains, were found in different RIP family members, and these domains should be keys in determining the specific function of each RIP kinase. It is known that RIP kinases participate in different biological processes, including those in innate immunity, but their downstream substrates are largely unknown. This review will give an overview of the structures and functions of RIP family members, and an update of recent progress in RIP kinase research. Cellular & Molecular Immunology (2010) 7, 243-249; doi:10.1038/cmi.2010.10; published online 12 April 2010
引用
收藏
页码：243 / 249
页数：7
相关论文
共 50 条
  • [21] Receptor-Interacting Protein Kinase-3 Expression Impacts Ocular Vascular Development and Pathological Neovascularization
    Song, Yong-Seok
    Wang, Shoujian
    Park, Sunyoung
    Hanna, Barbara
    Johnson, Kelsey J.
    Darjatmoko, Soesiawati R.
    Saghiri, Mohammad Ali
    Saghiri, Ali Mohammad
    Liu, Bo
    Sorenson, Christine M.
    Sheibani, Nader
    [J]. CELLS, 2024, 13 (24)
  • [22] Intrinsic cleavage of receptor-interacting protein kinase-1 by caspase-6
    B J van Raam
    D E Ehrnhoefer
    M R Hayden
    G S Salvesen
    [J]. Cell Death & Differentiation, 2013, 20 : 86 - 96
  • [23] Quizartinib inhibits necroptosis by targeting receptor-interacting serine/threonine protein kinase 1
    Li, Min
    Wei, Jun
    Zhu, Guofeng
    Fu, Shufang
    He, Xiaoyan
    Hu, Xinqian
    Yu, Yajie
    Mou, Yan
    Wang, Jia
    You, Xiaoling
    Xiao, Xin
    Gu, Tanrong
    Ye, Zhi
    Zha, Yunhong
    [J]. FASEB JOURNAL, 2023, 37 (10)
  • [24] Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis
    Kamarajan, Pachiyappan
    Alhazzazi, Turki Y.
    Danciu, Theodora
    D'silva, Nisha J.
    Verdin, Eric
    Kapila, Yvonne L.
    [J]. CANCER, 2012, 118 (23) : 5800 - 5810
  • [25] RIP3 β and RIP3 γ, two novel splice variants of receptor-interacting protein 3 (RIP3), downregulate RIP3-induced apoptosis
    Yang, YH
    Hu, WP
    Feng, SS
    Ma, J
    Wu, M
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2005, 332 (01) : 181 - 187
  • [26] Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
    Majdi, Amine
    Aoudjehane, Lynda
    Ratziu, Vlad
    Islam, Tawhidul
    Afonso, Marta B.
    Conti, Filomena
    Mestiri, Taieb
    Lagouge, Marie
    Foufelle, Fabienne
    Ballenghien, Florine
    Ledent, Tatiana
    Moldes, Marthe
    Cadoret, Axelle
    Fouassier, Laura
    Delaunay, Jean-Louis
    Ait-Slimane, Tounsia
    Courtois, Gilles
    Feve, Bruno
    Scatton, Olivier
    Prip-Buus, Carina
    Rodrigues, Cecilia M. P.
    Housset, Chantal
    Gautheron, Jeremie
    [J]. JOURNAL OF HEPATOLOGY, 2020, 72 (04) : 627 - 635
  • [27] Receptor-interacting protein kinase 3 deficiency inhibits immune cell infiltration and attenuates organ injury in sepsis
    Sharma, Archna
    Matsuo, Shingo
    Yang, Weng-Lang
    Wang, Zhimin
    Wang, Ping
    [J]. CRITICAL CARE, 2014, 18 (04)
  • [28] Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
    He, Sudan
    Liang, Yuqiong
    Shao, Feng
    Wang, Xiaodong
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (50) : 20054 - 20059
  • [29] TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8
    Ikner, Aminah
    Ashkenazi, Avi
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (24) : 21546 - 21554
  • [30] Expression and functional analysis of receptor-interacting serine/threonine kinase 2 (RIP2) in Japanese flounder (Paralichthys olivaceus)
    Liu, Jinxiang
    Cao, Dandan
    Liu, Yuezhong
    Li, Zan
    Si, Yu
    Wang, Zhigang
    Zhang, Quanqi
    Yu, Haiyang
    Wang, Xubo
    [J]. FISH & SHELLFISH IMMUNOLOGY, 2018, 75 : 327 - 335
12345