Pancreatic Adenocarcinoma

被引：1763

作者：

Ryan, David P. ^{[1
]}

Hong, Theodore S. ^{[2
]}

Bardeesy, Nabeel ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Dept Med, Div Hematol Oncol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2014年 / 371卷 / 11期

关键词：

PHASE-III TRIAL; INTRAEPITHELIAL NEOPLASIA; ADJUVANT CHEMOTHERAPY; POOLED ANALYSIS; EGF RECEPTOR; CANCER RISK; GEMCITABINE; KRAS; RESECTION; FAMILIES;

D O I：

10.1056/NEJMra1404198

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：1039 / 1049

页数：11

共 75 条

[41] Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer [J].

Lesina, Marina ;

Kurkowski, Magdalena U. ;

Ludes, Katharina ;

Rose-John, Stefan ;

Treiber, Matthias ;

Kloeppel, Guenter ;

Yoshimura, Akihiko ;

Reindl, Wolfgang ;

Sipos, Bence ;

Akira, Shizuo ;

Schmid, Roland M. ;

Alguel, Hana .

CANCER CELL, 2011, 19 (04) :456-469

[42] KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma [J].

Ling, Jianhua ;

Kang, Ya'an ;

Zhao, Ruiying ;

Xia, Qianghua ;

Lee, Dung-Fang ;

Chang, Zhe ;

Li, Jin ;

Peng, Bailu ;

Fleming, Jason B. ;

Wang, Huamin ;

Liu, Jinsong ;

Lemischka, Ihor R. ;

Hung, Mien-Chie ;

Chiao, Paul J. .

CANCER CELL, 2012, 21 (01) :105-120

[43] Gemcitabine Alone Versus Gemcitabine Plus Radiotherapy in Patients With Locally Advanced Pancreatic Cancer: An Eastern Cooperative Oncology Group Trial [J].

Loehrer, Patrick J., Sr. ;

Feng, Yang ;

Cardenes, Higinia ;

Wagner, Lynne ;

Brell, Joanna M. ;

Cella, David ;

Flynn, Patrick ;

Ramanathan, Ramesh K. ;

Crane, Christopher H. ;

Alberts, Steven R. ;

Benson, Al B., III .

JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (31) :4105-4112

[44] A Lethally Irradiated Allogeneic Granulocyte-Macrophage Colony Stimulating Factor-Secreting Tumor Vaccine for Pancreatic Adenocarcinoma: A Phase II Trial of Safety, Efficacy, and Immune Activation [J].

Lutz, Eric ;

Yeo, Charles J. ;

Lillemoe, Keith D. ;

Biedrzycki, Barbara ;

Kobrin, Barry ;

Herman, Joseph ;

Sugar, Elizabeth ;

Piantadosi, Steven ;

Cameron, John L. ;

Solt, Sara ;

Onners, Beth ;

Tartakovsky, Irena ;

Choi, Miri ;

Sharma, Rajni ;

Illei, Peter B. ;

Hruban, Ralph H. ;

Abrams, Ross A. ;

Le, Dung ;

Jaffee, Elizabeth ;

Laheru, Dan .

ANNALS OF SURGERY, 2011, 253 (02) :328-335

[45] Arterial and Venous Resection for Pancreatic Adenocarcinoma Operative and Long-term Outcomes [J].

Martin, Robert C. G., II ;

Scoggins, Charles R. ;

Egnatashvili, Vasili ;

Staley, Charles A. ;

McMasters, Kelly M. ;

Kooby, David A. .

ARCHIVES OF SURGERY, 2009, 144 (02) :154-159

[46] Vagaries of clinical presentation of pancreatic and biliary tract cancer [J].

Modolell, I ;

Guarner, L ;

Malagelada, JR .

ANNALS OF ONCOLOGY, 1999, 10 :82-84

[47] Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada clinical trials group [J].

Moore, Malcolm J. ;

Goldstein, David ;

Hamm, John ;

Figer, Arie ;

Hecht, Joel R. ;

Gallinger, Steven ;

Au, Heather J. ;

Murawa, Pawel ;

Walde, David ;

Wolff, Robert A. ;

Campos, Daniel ;

Lim, Robert ;

Ding, Keyue ;

Clark, Gary ;

Voskoglou-Nomikos, Theodora ;

Ptasynski, Mieke ;

Parulekar, Wendy .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (15) :1960-1966

[48] EGF Receptor Signaling Is Essential for K-Ras Oncogene-Driven Pancreatic Ductal Adenocarcinoma [J].

Navas, Carolina ;

Hernandez-Porras, Isabel ;

Schuhmacher, Alberto J. ;

Sibilia, Maria ;

Guerra, Carmen ;

Barbacid, Mariano .

CANCER CELL, 2012, 22 (03) :318-330

[49] CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer [J].

Neesse, Albrecht ;

Frese, Kristopher K. ;

Bapiro, Tashinga E. ;

Nakagawa, Tomoaki ;

Sternlicht, Mark D. ;

Seeley, Todd W. ;

Pilarsky, Christian ;

Jodrell, Duncan I. ;

Spong, Suzanne M. ;

Tuveson, David A. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (30) :12325-12330

[50] Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid vs Gemcitabine Following Pancreatic Cancer Resection A Randomized Controlled Trial [J].

Neoptolemos, John P. ;

Stocken, Deborah D. ;

Bassi, Claudio ;

Ghaneh, Paula ;

Cunningham, David ;

Goldstein, David ;

Padbury, Robert ;

Moore, Malcolm J. ;

Gallinger, Steven ;

Mariette, Christophe ;

Wente, Moritz N. ;

Izbicki, Jakob R. ;

Friess, Helmut ;

Lerch, Markus M. ;

Dervenis, Christos ;

Olah, Attila ;

Butturini, Giovanni ;

Doi, Ryuichiro ;

Lind, Pehr A. ;

Smith, David ;

Valle, Juan W. ;

Palmer, Daniel H. ;

Buckels, John A. ;

Thompson, Joyce ;

McKay, Colin J. ;

Rawcliffe, Charlotte L. ;

Buechler, Markus W. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 304 (10) :1073-1081

← 1 2 3 4 5 6 7 8 →