Fluorine-substituted hydroxyapatite scaffolds hydrothermally grown from aragonitic cuttlefish bones

被引：90

作者：

Kannan, S.

Rocha, J. H. G.

Agathopoulos, S.

Ferreira, J. M. F. ^{[1
]}

机构：

[1] Univ Aveiro, Dept Ceram & Glass Engn, CICECO, P-3810193 Aveiro, Portugal

[2] Prod Mat Ceramicos Lda, AGORAMAT, P-3070304 Mira, Portugal

[3] Univ Ioannina, Dept Mat Sci & Engn, GR-45110 Ioannina, Greece

来源：

ACTA BIOMATERIALIA | 2007年 / 3卷 / 02期

关键词：

hydrothermal transformation; aragonite; fluorapatite; cuttlefish bone; scaffolds;

D O I：

10.1016/j.actbio.2006.09.006

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Porous hydroxyapatite scaffolds with different levels of fluorine substitution (46% and 85%) on the OH sites were produced via hydrothermal transformation of aragonitic cuttlefish bones at 200 degrees C and calcination at temperatures up to 1200 degrees C. The increasing level of F substitution reduces the kinetics and probably the yield of the reaction. The incorporation of F in the lattice of hydroxypatite caused a lowering of the unit cell volume due to reduction of the length of the a-axis. The crystallites formed were close in size to bone-like apatite and were orientated along the a-axis rather than the c-axis. There was evidence of AB-type carbonated apatite. (c) 2006 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：243 / 249

页数：7

共 65 条

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