Parathyroid venous sampling for the preoperative localisation of parathyroid adenoma in patients with primary hyperparathyroidism

被引：7

作者：

Ho, Joon ^{[1
]}

Kim, Donggyu ^{[1
]}

Lee, Ji-Eun ^{[1
]}

Hong, Namki ^{[2
]}

Kim, Byung Moon ^{[3
]}

Kim, Dong Joon ^{[3
]}

Kim, Jinkyong ^{[1
]}

Lee, Cho Rok ^{[4
]}

Kang, Sang-Wook ^{[1
]}

Jeong, Jong Ju ^{[1
]}

Nam, Kee-Hyun ^{[1
]}

Chung, Woong Youn ^{[1
]}

Rhee, Yumie ^{[2
]}

机构：

[1] Yonsei Univ, Severance Hosp, Yonsei Canc Ctr, Dept Surg,Coll Med, Seoul 03722, South Korea

[2] Yonsei Univ, Severance Hosp, Endocrine Res Inst, Dept Internal Med,Coll Med, Seoul, South Korea

[3] Yonsei Univ, Severance Hosp, Dept Radiol, Coll Med, Seoul, South Korea

[4] Yonsei Univ, Yongin Severance Hosp, Dept Surg, Coll Med, Yongin, South Korea

来源：

SCIENTIFIC REPORTS | 2022年 / 12卷 / 01期

关键词：

FINE-NEEDLE-ASPIRATION; HORMONE; PERSISTENT; RECURRENT; SONOGRAPHY; GUIDELINES; UTILITY; ASSAY;

D O I：

10.1038/s41598-022-11238-0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Preoperative localisation studies are essential for parathyroidectomy in patients with primary hyperparathyroidism. If the location of abnormal parathyroid glands cannot be identified through non-invasive studies, parathyroid venous sampling (PVS) may be employed. In this study, we evaluated the utility of preoperative PVS in parathyroid surgery. Patients with primary hyperparathyroidism who underwent preoperative PVS at Severance Hospital between January 2015 and June 2020 were identified. Patients for whom the results of non-invasive imaging studies were inconsistent or negative underwent PVS. The results of PVS were compared with operative findings and pathologic results. For 14 patients, the results of preoperative ultrasonography and Tc-99m-sestamibi single-photon emission computed tomography (SPECT) were negative; for 20 patients, either the result of only one test was positive, or the results of the two tests were inconsistent. With respect to the lateralisation of diseased adenoma, the results of PVS and pathological examination were inconsistent only for one patient in either group (total: 2/34 patients). This study showed that PVS could be used effectively for preoperative localisation in patients with primary hyperparathyroidism in whom the location of diseased parathyroid glands cannot be determined through non-invasive image studies.

引用

页数：7

共 38 条

[1]

Abraham Devaprabu, 2007, Endocr Pract, V13, P333

[2] Utility of intraoperative bilateral internal jugular venous sampling with rapid parathyroid hormone testing in guiding patients with a negative sestamibi scan for minimally invasive parathyroidectomy-a randomized controlled trial [J].