An efficient method for the conversion of aromatic and aliphatic nitriles to the corresponding N-tert-butyl amides:: a modified Ritter reaction

被引：77

作者：

Reddy, KL ^{[1
]}

机构：

[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Proc Res & Dev, Wallingford, CT 06492 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 07期

关键词：

modified Ritter reaction; nitriles; tert-butyl acetate; N-tert-butyl amides;

D O I：

10.1016/S0040-4039(03)00006-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic and aliphatic nitriles react with tert-butyl acetate in the presence of a catalytic amount of sulfuric acid to give the corresponding N-tert-butyl amides in excellent yields. (C) 2003 Published by Elsevier Science Ltd.

引用

页码：1453 / 1455

页数：3

共 17 条

[1] CONVERSION OF ALCOHOLS INTO AMIDES USING CHLORODIPHENYLMETHYLIUM HEXACHLOROANTIMONATE IN NITRILE SOLVENTS [J].

BARTON, DHR ;

MAGNUS, PD ;

YOUNG, RN .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1973, (10) :331-332

[2]

Benson F. R., 1949, J AM CHEM SOC, V71, P4128, DOI DOI 10.1021/JA01180A075

[3]

EUGENE EM, Patent No. 72773

[4]

FIROUZABADI H, 1997, SYNTHETIC COMMUN, V27, P2403

[5]

IKEDA K, Patent No. 200090274

[6]

IKEDA K, 2000, Patent No. 20001102

[7]

IKEDA K, 2000, Patent No. 0064430

[8]

IKEDA K, Patent No. 20000329

[9]

Krimen L. I., 1969, ORG REACT, V17, P213, DOI DOI 10.1002/0471264180.0R017.03

[10] Fe3+-montmorillonite K10:: An efficient catalyst for selective amidation of alcohols with nitriles under non-aqueous condition [J].

Lakouraj, MM ;

Movassagh, B ;

Fasihi, J .

SYNTHETIC COMMUNICATIONS, 2000, 30 (05) :821-827

← 1 2 →