Efficacy, cost-minimization, and budget impact of a personalized discharge letter for basal cell carcinoma patients to reduce low-value follow-up care

被引:4
作者
van Egmond, Sven [1 ]
van Vliet, Ella D. [2 ]
Wakkee, Marlies [1 ]
Hollestein, Loes M. [1 ,3 ]
Pouwels, Xavier G. L., V [2 ]
Koffijberg, Hendrik [2 ]
Misirli, Yesim [3 ]
Bakkum, Rachel S. L. A. [4 ]
Bastiaens, Maarten T. [5 ]
Kukutsch, Nicole A. [6 ]
Oosting, Albert J. [7 ]
Plasmeijer, Elsemieke, I [8 ]
van Rengen, Annik [9 ]
de Roos, Kees-Peter [10 ]
Nijsten, Tamar E. C. [1 ]
de Vries, Esther [11 ]
de Bekker-Grob, Esther W. [12 ]
机构
[1] Erasmus MC Canc Inst, Dept Dermatol, Rotterdam, Netherlands
[2] Univ Twente, Dept Hlth Technol & Serv Res, Enschede, Netherlands
[3] Netherlands Comprehens Canc Org IKNL, Dept Res, Utrecht, Netherlands
[4] Alrijne Ziekenhuis, Dept Dermatol, Leiderdorp, Netherlands
[5] Elisabeth TweeSteden Hosp, Dept Dermatol, Tilburg, Netherlands
[6] Leiden Univ, Dept Dermatol, Med Ctr, Leiden, Netherlands
[7] Spaarne Ziekenhuis, Dept Dermatol, Hoofddorp, Netherlands
[8] Antoni van Leeuwenhoek, Dept Dermatol, Netherlands Canc Inst, Amsterdam, Netherlands
[9] Mohs Klinieken, Dept Dermatol, Dordrecht, Netherlands
[10] DermaPark, Dept Dermatol, Uden, Netherlands
[11] Pontificia Univ Javeriana, Dept Clin Epidemiol & Biostat, Bogota, Colombia
[12] Erasmus Univ, Erasmus Sch Hlth Policy & Management, Rotterdam, Netherlands
关键词
KERATINOCYTE CARCINOMA; ISPOR; IMPLEMENTATION; TRENDS; TRIALS; RISK;
D O I
10.1371/journal.pone.0260978
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background The incidence of keratinocyte carcinomas is high and rapidly growing. Approximately 80% of keratinocyte carcinomas consist of basal cell carcinomas (BCC) with 50% of these being considered as low-risk tumors. Nevertheless, 83% of the low-risk BCC patients were found to receive more follow-up care than recommended according to the Dutch BCC guideline, which is one visit post-treatment for this group. More efficient management could reduce unnecessary follow-up care and related costs. Objectives To study the efficacy, cost-utility, and budget impact of a personalized discharge letter for low-risk BCC patients compared with usual care (no personalized letter). Methods In a multi-center intervention study, a personalized discharge letter in addition to usual care was compared to usual care in first-time BCC patients. Model-based cost-utility and budget impact analyses were conducted, using individual patient data gathered via surveys. The outcome measures were number of follow-up visits, costs and quality adjusted life years (QALY) per patient. Results A total of 473 first-time BCC patients were recruited. The personalized discharge letter decreased the number of follow-up visits by 14.8% in the first year. The incremental costs after five years were -Euro24.45 per patient. The QALYs were 4.12 after five years and very similar in both groups. The national budget impact was -Euro2,7 million after five years. Conclusions The distribution of a personalized discharge letter decreases the number of unnecessary follow-up visits and implementing the intervention in a large eligible population would results in substantial cost savings, contributing to restraining the growing BCC costs.
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页数:14
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