ETE 3: Reconstruction, Analysis, and Visualization of Phylogenomic Data

被引:1257
作者
Huerta-Cepas, Jaime [1 ]
Serra, Francois [2 ]
Bork, Peer [1 ,3 ,4 ,5 ]
机构
[1] European Mol Biol Lab, Struct & Computat Biol Unit, Heidelberg, Germany
[2] UPF, Ctr Genom Regulat, Ctr Nacl Anal Genom CNAG CRG, Barcelona 08028, Spain
[3] Univ Heidelberg Hosp, Germany Mol Med Partnership Unit MMPU, D-69117 Heidelberg, Germany
[4] European Mol Biol Lab, D-69117 Heidelberg, Germany
[5] Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany
关键词
phylogenomics; tree visualization; tree comparison; NCBI taxonomy; hypothesis testing; phylogenetics; CODON-SUBSTITUTION MODELS; POSITIVE SELECTION; LIKELIHOOD METHOD; TREE; SITES; LIFE; TOOLKIT;
D O I
10.1093/molbev/msw046
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Environment for Tree Exploration (ETE) is a computational framework that simplifies the reconstruction, analysis, and visualization of phylogenetic trees and multiple sequence alignments. Here, we present ETE v3, featuring numerous improvements in the underlying library of methods, and providing a novel set of standalone tools to perform common tasks in comparative genomics and phylogenetics. The new features include (i) building gene-based and supermatrix-based phylogenies using a single command, (ii) testing and visualizing evolutionary models, (iii) calculating distances between trees of different size or including duplications, and (iv) providing seamless integration with the NCBI taxonomy database. ETE is freely available at http://etetoolkit.org
引用
收藏
页码:1635 / 1638
页数:4
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