Clinicopathologic Characteristics of Cervical Cancer Patients at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, January 2012-December 2016

Introduction: Cervical cancer is the second most common cancer among women in Indonesia with 20,928 number of incidence and 20 deaths per day. Most of these patients came at an advanced stage (>= Stage IIB) with lower rate of life expectancy compared with early stage. Aim: To review clinicopathologic characteristics of cervical cancer patients at Dr. Cipto Mangunkusumo Hospital, Jakarta. Method: This retrospective study involved 1,709 patients with cervical cancer at Dr. Cipto Mangunkusumo Hospital who are registered at the Cancer Registration Information System from January 2012 to December 2016. Tumor size was measured using ultrasonography (USG). Histological type, differentiation, and lymphovascular space involvement (LVSI) were confirmed by histopathology examination. Staging was done using the International Federation of Gynecology and Obstetrics (FIGO) classification. Result: The highest incidence was in 35-64 years (87.02%) with the peak incidence in 50-54 years (21.12%). 1,274 patients have multiparity status (74.55%). There were 336 patients identified at early stage (19,66%) and 1,373 patients at late stage (80,34%). Tumor size <= 4 cm was found in 535 patients (31.30%) and >4 cm in 1,174 patients (68.70%). 75.71% had squamous cell carcinoma (SCC) with moderately differentiated (61.61%) and absent LVSI (82.15%). Conclusion: Most of patients were in the age range 40-59 years (69.81%) with multiparity status and had tumor size >4 cm. Based on this study 80.34% patients presented at an advanced stage. The most histological type found was SCC, moderately differentiated with absent LVSI.