Management of Radiation Proctitis

被引：14
作者：
Mendenhall, William M. [1 ]
McKibben, Brian T. [2 ]
Hoppe, Bradford S. [1 ]
Nichols, Romaine C. [1 ]
Henderson, Randal H. [1 ]
Mendenhall, Nancy P. [1 ]
机构：
[1] Univ Florida, Proton Therapy Inst, Jacksonville, FL USA
[2] St Vincents Healthcare, Jacksonville, FL USA
来源：
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 2014年 / 37卷 / 05期
关键词：
radiation therapy; review; toxicities; complications; ARGON PLASMA COAGULATION; INDUCED HEMORRHAGIC PROCTITIS; HYPERBARIC-OXYGEN THERAPY; TERM-FOLLOW-UP; ND-YAG LASER; DOUBLE-BLIND; PROSTATE-CANCER; INDUCED PROCTOSIGMOIDITIS; PERCENT FORMALIN; CONTROLLED TRIAL;
D O I：
10.1097/COC.0b013e318271b1aa
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The optimal management of radiation proctitis is ill defined. A variety of alternatives are available and include topical agents (ie, sucralfate enemas, formalin), oral agents (ie, pentoxyfylline, vitamin A), hyperbaric oxygen, and endoscopic interventions (ie, argon plasma coagulation). It is prudent to manage patients conservatively and to intervene only when necessary with the option least likely to exacerbate the proctitis. Rectal biopsies should be avoided as they may precipitate a complication. More aggressive measures, such as argon laser coagulation, should be employed only when more conservative approaches fail.
引用
收藏
页码：517 / 523
页数：7
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