Disseminated Mycobacterium peregrinum infection in a child with complete interferon-gamma receptor-1 deficiency

被引：1
作者：
Koscielniak, E [1 ]
de Boer, T
Dupuis, S
Naumann, L
Casanova, JL
Ottenhoff, THM
机构：
[1] Olga Hosp, Dept Oncol Haematol, Stuttgart, Germany
[2] Leiden Univ, Ctr Med, Dept Immunohaematol & Blood Transfus, Leiden, Netherlands
[3] Unite Immunol & Hematol, Lab Genet Humainedes Malad Infect, Paris, France
[4] Univ Regensburg, Inst Med Mikrobiol & Hyg, D-8400 Regensburg, Germany
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2003年 / 22卷 / 04期
关键词：
interferon-gamma receptor-1 deficiency; Mycobacterium peregrinum infection; disseminated mycobacterial disease; infection and interferon-gamma receptor-1 deficiency;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We describe an infant who at the age of 1 year developed chronic disseminating infection caused by a fast growing, poorly pathogenic mycobacterial species, Mycobacterium peregrinum. The child was diagnosed with complete interferon-gamma receptor-1 deficiency resulting from a novel, recessive null mutation in IFNGR1. This is only the second reported case of interferon-gamma receptor-1 deficiency in which the primary infection was caused by a fast growing mycobacterial species.
引用
收藏
页码：378 / 380
页数：3
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