Overdiagnosis and overtreatment of early detected prostate cancer

被引：125

作者：

Bangma, C. H. ^{[1
]}

Roemeling, S. ^{[1
]}

Schroder, F. H. ^{[1
]}

机构：

[1] Erasmus Univ, Med Ctr, Dept Urol, NL-3000 DR Rotterdam, Netherlands

来源：

WORLD JOURNAL OF UROLOGY | 2007年 / 25卷 / 01期

关键词：

rationale for screening; overdiagnosis; overtreatment; prostate cancer; active surveillance;

D O I：

10.1007/s00345-007-0145-z

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Early detection of prostate cancer is associated with the diagnosis of a considerable proportion of cancers that are indolent, and that will hardly ever become symptomatic during lifetime. Such overdiagnosis should be avoided in all forms of screening because of potential adverse psychological and somatic side effects. The main threat of overdiagnosis is overtreatment of indolent disease. Men with prostate cancer that is likely to be indolent may be offered active surveillance. Evaluation of active surveillance studies and validation of new biological parameters for risk assessment are expected.

引用

页码：3 / 9

页数：7

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