siRNAs and miRNAs: small RNA molecules for big tasks

被引：3
作者：
Lesicka, J [1 ]
Piontek, P [1 ]
Szweykowska-Kulinska, Z [1 ]
Jarmolowski, A [1 ]
机构：
[1] Adam Mickiewicz Univ, Inst Mol Biol & Biotechnol, Dept Gene Express, PL-60371 Poznan, Poland
来源：
ACTA PHYSIOLOGIAE PLANTARUM | 2004年 / 26卷 / 03期
关键词：
development; gene silencing; miRNA; plant; PTGS; siRNA;
D O I：
10.1007/s11738-004-0026-7
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Small RNAs have been recently discovered as important regulators of gene expression in Eukaryota, This review compares two categories of small RNAs existing in plants: short interfering RNAs (siRNAs) and microRNAs (miRNAs) and reveals similarities and differences between two intriguing processes: RNA degradation and translational repression directed by small RNAs. The disruption of miRNA-mediated regulation causes developmental abnormalities in plants, proving a fundamental role of miRNAs.
引用
收藏
页码：363 / 368
页数：6
相关论文
共 37 条
  • [1] Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes
    Aukerman, MJ
    Sakai, H
    [J]. PLANT CELL, 2003, 15 (11) : 2730 - 2741
  • [2] MicroRNAs: At the root of plant development?
    Bartel, B
    Bartel, DP
    [J]. PLANT PHYSIOLOGY, 2003, 132 (02) : 709 - 717
  • [3] Role of microRNAs in plant and animal development
    Carrington, JC
    Ambros, V
    [J]. SCIENCE, 2003, 301 (5631) : 336 - 338
  • [4] A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development
    Chen, XM
    [J]. SCIENCE, 2004, 303 (5666) : 2022 - 2025
  • [5] The TCP domain: a motif found in proteins regulating plant growth and development
    Cubas, P
    Lauter, N
    Doebley, J
    Coen, E
    [J]. PLANT JOURNAL, 1999, 18 (02) : 215 - 222
  • [6] An RNA-Dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus
    Dalmay, T
    Hamilton, A
    Rudd, S
    Angell, S
    Baulcombe, DC
    [J]. CELL, 2000, 101 (05) : 543 - 553
  • [7] siRNAs can function as miRNAs
    Doench, JG
    Petersen, CP
    Sharp, PA
    [J]. GENES & DEVELOPMENT, 2003, 17 (04) : 438 - 442
  • [8] RNA interference is mediated by 21-and 22-nucleotide RNAs
    Elbashir, SM
    Lendeckel, W
    Tuschl, T
    [J]. GENES & DEVELOPMENT, 2001, 15 (02) : 188 - 200
  • [9] Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C-elegans developmental timing
    Grishok, A
    Pasquinelli, AE
    Conte, D
    Li, N
    Parrish, S
    Ha, I
    Baillie, DL
    Fire, A
    Ruvkun, G
    Mello, CC
    [J]. CELL, 2001, 106 (01) : 23 - 34
  • [10] A species of small antisense RNA in posttranscriptional gene silencing in plants
    Hamilton, AJ
    Baulcombe, DC
    [J]. SCIENCE, 1999, 286 (5441) : 950 - 952
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