Bioprinting technology and its applications

被引：219

作者：

Seol, Young-Joon ^{[1
]}

Kang, Hyun-Wook ^{[1
]}

Lee, Sang Jin ^{[1
]}

Atala, Anthony ^{[1
]}

Yoo, James J. ^{[1
]}

机构：

[1] Wake Forest Sch Med, Wake Forest Inst Regenerat Med, Winston Salem, NC 27157 USA

来源：

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 2014年 / 46卷 / 03期

关键词：

Bioprinting; Reconstruction; Regenerative medicine; SOLID FREEFORM FABRICATION; VALVE CONDUITS; STEM-CELLS; TISSUE; SCAFFOLDS; HYDROGELS; BIOFABRICATION; CONSTRUCTION; REGENERATION; VIABILITY;

D O I：

10.1093/ejcts/ezu148

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bioprinting technology has emerged as a powerful tool for building tissue and organ structures in the field of tissue engineering. This technology allows precise placement of cells, biomaterials and biomolecules in spatially predefined locations within confined three-dimensional (3D) structures. Various bioprinting technologies have been developed and utilized for applications in life sciences, ranging from studying cellular mechanisms to constructing tissues and organs for implantation, including heart valve, myocardial tissue, trachea and blood vessels. In this article, we introduce the general principles and limitations of the most widely used bioprinting technologies, including jetting- and extrusion-based systems. Application-based research focused on tissue regeneration is presented, as well as the current challenges that hamper clinical utility of bioprinting technology.

引用

页码：342 / 348

页数：7

共 63 条

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