Near-Infrared Imaging Using Intravenous Indocyanine Green at a Conventional Dose to Locate Pulmonary Metastases: A Pilot Study

被引:5
|
作者
Hamaji, Masatsugu [1 ]
Chen-Yoshikawa, Toyofumi Fengshi [1 ]
Minami, Manabu [2 ]
Date, Hiroshi [1 ]
机构
[1] Kyoto Univ, Kyoto Univ Hosp, Dept Thorac Surg, Sakyo Ku, Kyoto, Japan
[2] Kyoto Univ, Kyoto Univ Hosp, Dept Clin Innovat Med, Sakyo Ku, Kyoto, Japan
来源
THORACIC AND CARDIOVASCULAR SURGEON | 2019年 / 67卷 / 08期
关键词
pulmonary metastasis; clinical trial; near-infrared; INJECTION;
D O I
10.1055/s-0038-1675346
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Intravenous indocyanine green (ICG) has been reported to localize intra-abdominal metastatic lesions in several clinical trials. Our pilot study aimed to investigate the feasibility and safety of ICG fluorescence localization in pulmonary metastasectomy using a near-infrared fluorescence thoracoscope. Each patient received intravenous 0.25 or 0.5 mg/kg of ICG. The maximum diameter of the tumor on computed tomography ranged from 0.5 to 3.5 (median: 1.15) cm. Intravenous ICG injection localized pulmonary metastases in a portion (3 patients) of the enrolled patients. Our preliminary results provided us with important information to modify the study protocol.
引用
收藏
页码:688 / 691
页数:4
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