Disruption of transepithelial resistance by enterotoxigenic Escherichia coli

被引：38
作者：
Johnson, Amber M. [2 ,3 ]
Kaushik, Radhey S. [2 ,3 ]
Hardwidge, Philip R. [1 ]
机构：
[1] Univ Kansas, Med Ctr, Dept Microbiol Mol Genet & Immunol, Kansas City, KS 66160 USA
[2] S Dakota State Univ, Dept Vet Sci, Brookings, SD 57007 USA
[3] S Dakota State Univ, Dept Biol & Microbiol, Brookings, SD 57007 USA
来源：
VETERINARY MICROBIOLOGY | 2010年 / 141卷 / 1-2期
关键词：
Bacterial pathogenesis; Enterotoxigenic Escherichia call; Tight junction; Transepithelial resistance; JUNCTION BARRIER FUNCTION; HEAT-LABILE ENTEROTOXIN; TIGHT-JUNCTION; IN-VITRO; STRAIN; CELLS; PATHOGENESIS; DYSFUNCTION; ADHERENCE; MUTANT;
D O I：
10.1016/j.vetmic.2009.08.020
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Transepithelial resistance and tight junction protein localization in porcine intestinal epithelial cells were evaluated as a function of infection with porcine enterotoxigenic Escherichia coli isolates differing in adhesin and enterotoxin profiles. Robust heat-labile enterotoxin-independent reduction of host transepithelial resistance was observed in the absence of tight junction protein mislocalization. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：115 / 119
页数：5
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