Coenzyme Q10 level in plasma of children with inflammatory process

被引：0
作者：
Mikoluc, B [1 ]
Karpinska, J [1 ]
Motkowski, R [1 ]
Piotrowska-Jastrzebska, J [1 ]
机构：
[1] Med Acad Bialystok, Dept Propedeut Pediat, PL-15274 Bialystok, Poland
来源：
METAL IONS IN BIOLOGY AND MEDICINE, VOL 7 | 2002年 / 7卷
关键词：
coenzyme Q(10) level; pediatric population; acute inflammatory process;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Using a newly developed metod by HPLC with ultraviolet detection we measured plasma coenzyme Q(10) (CoQ(10)) level in group of 43 children (19 fernals and 24 males: ages 1 month 9 years) with an acute inflammatory process. The results for coenzyme Q(10) were expressed as molar concentration (mumol/l plasma). Our study confirmed that CoQ(10) concentration (median 0.8 mumol/l) was independent of sex, and we established which biochemical parameters influence on ubiquinone levels. The results indicate that CoQ(10) concentration is connected with leukocytosis, calcium and magnesium levels. These findings suggested that transferin, amylase and serum glutamic transaminase may also determine the CoQ(10)-levels plasma.
引用
收藏
页码：421 / 426
页数：6
相关论文
共 11 条
  • [1] Artuch R, 1998, CLIN CHEM, V44, P2378
  • [2] BIOCHEMICAL, PHYSIOLOGICAL AND MEDICAL ASPECTS OF UBIQUINONE FUNCTION
    ERNSTER, L
    DALLNER, G
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1995, 1271 (01): : 195 - 204
  • [3] SURVIVAL OF CANCER-PATIENTS ON THERAPY WITH COENZYME-Q(10)
    FOLKERS, K
    BROWN, R
    JUDY, WV
    MORITA, M
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 192 (01) : 241 - 245
  • [4] Gvozdjakova A, 1994, Bratisl Lek Listy, V95, P443
  • [5] Jolliet P, 1998, INT J CLIN PHARM TH, V36, P506
  • [6] Kaplan P, 1996, PHYSIOL RES, V45, P39
  • [7] LELLI JL, 1993, CIRC SHOCK, V39, P178
  • [8] Vitamin E and coenzyme Q concentrations in the thyroid tissues of patients with various thyroid disorders
    Mano, T
    Iwase, K
    Hayashi, R
    Hayakawa, N
    Uchimura, K
    Makino, M
    Nagata, M
    Sawai, Y
    Oda, N
    Hamada, M
    Aono, T
    Nakai, A
    Nagasaka, A
    Itoh, M
    [J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1998, 315 (04) : 230 - 232
  • [9] Coenzyme Q10 fetal plasma levels
    Noia, G
    Romano, D
    De Santis, M
    Mariorenzi, S
    Caruso, A
    Mancuso, S
    [J]. FETAL DIAGNOSIS AND THERAPY, 1998, 13 (02) : 127 - 130
  • [10] The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation
    Suzuki, S
    Hinokio, Y
    Ohtomo, M
    Hirai, M
    Hirai, A
    Chiba, M
    Kasuga, S
    Satoh, Y
    Akai, H
    Toyota, T
    [J]. DIABETOLOGIA, 1998, 41 (05) : 584 - 588
12