HAND, FOOT AND MOUTH DISEASE CAUSED BY COXSACKIEVIRUS A6, BEIJING, 2013

被引:70
作者
Gu Hongyan [1 ]
Ma Chengjie [2 ]
Yang Qiaozhi [3 ]
Hua Wenhao [2 ]
Li Juan [2 ]
Pang Lin [2 ]
Xu Yanli [2 ]
Wei Hongshan [2 ]
Li Xingwang [1 ,2 ]
机构
[1] Peking Univ, Teaching Hosp, Beijing Ditan Hosp, Beijing 100015, Peoples R China
[2] Capital Med Univ, Beijing Ditan Hosp, Beijing, Peoples R China
[3] Liaocheng City Hosp, Liaocheng, Shandong, Peoples R China
关键词
hand; foot and mouth disease; enterovirus; coxsackievirus A6; 71; ONYCHOMADESIS;
D O I
10.1097/INF.0000000000000467
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Specimens and clinical data were collected from 243 hand, foot and mouth disease patients in Beijing in 2013. In total, 130 stool specimens were genotyped for enterovirus. Hand, foot and mouth disease was mainly detected in suburban areas and at the edges of urban areas between May and August. Coxsackievirus (CV) A6 replaced enterovirus (EV) 71 and CVA16, becoming the main causative agent of hand, foot and mouth disease. CVA6 infection led to significantly reduced fever duration and glucose levels compared with EV71 infection.
引用
收藏
页码:1302 / 1303
页数:2
相关论文
共 13 条
[1]   Enterovirus Co-infections and Onychomadesis after Hand, Foot, and Mouth Disease, Spain, 2008 [J].
Bracho, Maria A. ;
Gonzalez-Candelas, Fernando ;
Valero, Ana ;
Cordoba, Juan ;
Salazar, Antonio .
EMERGING INFECTIOUS DISEASES, 2011, 17 (12) :2223-2231
[2]   Nail matrix arrest following hand-foot-mouth disease: A report of five children [J].
Clementz, GC ;
Mancini, AJ .
PEDIATRIC DERMATOLOGY, 2000, 17 (01) :7-11
[3]   Atypical hand, foot, and mouth disease: a vesiculobullous eruption caused by Coxsackie virus A6 [J].
Feder, Henry M., Jr. ;
Bennett, Nicholas ;
Modlin, John F. .
LANCET INFECTIOUS DISEASES, 2014, 14 (01) :83-86
[4]   Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6, Japan, 2011 [J].
Fujimoto, Tsuguto ;
Iizuka, Setsuko ;
Enomoto, Miki ;
Abe, Katsuhiko ;
Yamashita, Kazuyo ;
Hanaoka, Nozomu ;
Okabe, Nobuhiko ;
Yoshida, Hiromu ;
Yasui, Yoshinori ;
Kobayashi, Masaaki ;
Fujii, Yoshiki ;
Tanaka, Hiroko ;
Yamamoto, Miwako ;
Shimizu, Hiroyuki .
EMERGING INFECTIOUS DISEASES, 2012, 18 (02) :337-339
[5]   Circulation of multiple enterovirus serotypes causing hand, foot and mouth disease in India [J].
Gopalkrishna, V. ;
Patil, Pooja R. ;
Patil, Gajanan P. ;
Chitambar, Shobha D. .
JOURNAL OF MEDICAL MICROBIOLOGY, 2012, 61 (03) :420-425
[6]   Clinical and epidemiologic features of Coxsackievirus A6 infection in children in northern Taiwan between 2004 and 2009 [J].
Lo, Shih-Hsuan ;
Huang, Yhu-Chering ;
Huang, Chung-Guei ;
Tsao, Kuo-Chien ;
Li, Wen-Chen ;
Hsieh, Yu-Chia ;
Chiu, Cheng-Hsun ;
Lin, Tzou-Yien .
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2011, 44 (04) :252-257
[7]   Species-specific RT-PCR amplification of human enteroviruses:: a tool for rapid species identification of uncharacterized enteroviruses [J].
Oberste, MS ;
Maher, K ;
Williams, AJ ;
Dybdahl-Sissoko, N ;
Brown, BA ;
Gookin, MS ;
Peñaranda, S ;
Mishrik, N ;
Uddin, M ;
Pallansch, MA .
JOURNAL OF GENERAL VIROLOGY, 2006, 87 :119-128
[8]   Coxsackievirus A6 and Hand, Foot, and Mouth Disease, Finland [J].
Osterback, Riikka ;
Vuorinen, Tytti ;
Linna, Mervi ;
Susi, Petri ;
Hyypia, Tirno ;
Waris, Matti .
EMERGING INFECTIOUS DISEASES, 2009, 15 (09) :1485-1488
[9]  
Qian HQ, 2013, INT J VIROL, V20, P6
[10]   An outbreak of coxsackievirus A6 hand, foot, and mouth disease associated with onychomadesis in Taiwan, 2010 [J].
Wei, Sung-Hsi ;
Huang, Yuan-Pin ;
Liu, Ming-Chih ;
Tsou, Tsung-Pei ;
Lin, Hui-Chen ;
Lin, Tsuey-Li ;
Tsai, Chen-Yen ;
Chao, Yen-Nan ;
Chang, Luan-Yin ;
Hsu, Chun-Ming .
BMC INFECTIOUS DISEASES, 2011, 11