Iatrogenic Toxicities in the Intensive Care Unit

被引：1

作者：

Nazer, Lama H. ^{[1
]}

Brown, Anne Rain T. ^{[2
]}

Awad, Wedad ^{[1
]}

机构：

[1] King Hussein Canc Ctr, Queen Rania Al Abdallah St,POB 1269, Amman 11941, Jordan

[2] Univ Texas MD Anderson Canc Ctr, 1515 Holcombe Blvd, Houston, TX 77030 USA

来源：

CRITICAL CARE CLINICS | 2021年 / 37卷 / 03期

关键词：

Iatrogenic disease; Drug-related side effects and adverse reactions; Adverse drug reactions; Critical illness; Intensive care units; ACUTE KIDNEY INJURY; CRITICALLY-ILL PATIENTS; PROPYLENE-GLYCOL; METABOLIC-ACIDOSIS; RISK-FACTORS; HEARING-LOSS; RHABDOMYOLYSIS; METHEMOGLOBINEMIA; OTOTOXICITY; PATHOPHYSIOLOGY;

D O I：

10.1016/j.ccc.2021.03.008

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Drug-induced iatrogenic toxicities are common in critically ill patients and have been associated with increased morbidity and mortality. Critically ill patients are at increased risk of iatrogenic toxicities due to the underlying critical illness, comorbidities, complexity of care, and increased number of administered medications. Early recognition and management of iatrogenic toxicities is essential.1,2 This review discusses several types of iatrogenic toxicities associated with medications used in the intensive care unit (ICU). We describe the mechanism of such toxicities, clinical presentation and diagnosis, as well as management. Although intravenous fluids and parenteral nutrition are considered drug therapy, this review

引用

页码：625 / 641

页数：17

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