One-Pot Synthesis of Benzothiazole-Tethered Chromanones/Coumarins via Claisen Rearrangement Using the Solid State Melt Reaction

被引：23

作者：

Bakthadoss, Manickam ^{[1
]}

Selvakumar, Raman ^{[2
]}

机构：

[1] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

[2] Univ Madras, Dept Organ Chem, Guindy Campus, Madras 600025, Tamil Nadu, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 81卷 / 08期

关键词：

BAYLIS-HILLMAN ADDUCTS; STEREOSELECTIVE-SYNTHESIS; REACTION SSMR; CYCLOADDITION; SCAFFOLDS; TETRA; TRANSFORMATIONS; ARCHITECTURES; CONSTRUCTION; CHEMISTRY;

D O I：

10.1021/acs.joc.5b02920

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel protocol has been successfully established for the efficient synthesis of benzothiazole-tethered chromanone/coumarin scaffolds via Claisen rearrangement using a solid state melt reaction in a one-pot manner. Benzothiazole formation and Claisen rearrangement involve the cleavage of S-S and C-O bonds and formation of C-S, C=N, and C-C bonds in a single operation without using a catalyst or solvent.

引用

页码：3391 / 3399

页数：9

共 43 条

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